Formulation for fast dissolution of lipophilic compounds

• US 20050266088A1
• Filed: 06/10/2005
• Published: 12/01/2005
• Est. Priority Date: 12/13/2002
• Status: Abandoned Application

• Current Assignee: Rijksuniversiteit Groningen
• Original Assignee: Rijksuniversiteit Groningen
• Inventors: van Drooge, Dirk Jan, Frijlink, Henderik Willem, Hinrichs, Wouter Leonardus Joseph
• Application Number:
  US11/149,930
• Publication Number:
  US 20050266088A1
• Time in Patent Office: Days
• US Class Current: 424/488
• CPC Class Codes: A61K 31/4422 1,4-Dihydropyridines, e.g. nifedipine, nicardipine
• CPC Class Codes: A61K 31/5513 1,4-Benzodiazepines, e.g. diazepam or clozapine
• CPC Class Codes: A61K 9/145 with organic compounds
• CPC Class Codes: A61K 9/146 with organic macromolecular compounds
• CPC Class Codes: A61K 9/2018 Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
• CPC Class Codes: A61K 9/205 Polysaccharides, e.g. alginate, gums; Cyclodextrin
• CPC Class Codes: A61K 9/2095 Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing mechanical aspects A61J3/00

Abstract

The present invention relates to a pharmaceutical composition comprising at least one lipophilic compound and at least one glass of a sugar, a sugar alcohol, a mixture of sugars, a mixture of sugar alcohols, or a mixture of at least one sugar and at least one sugar alcohol, wherein the lipophilic compound is incorporated in the sugar glass. The present invention further relates to a method for manufacturing such a pharmaceutical composition.

Claims