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Process isolation of withaferin-A from plant materials and products therefrom

  • US 20050266100A1
  • Filed: 03/30/2004
  • Published: 12/01/2005
  • Est. Priority Date: 03/30/2004
  • Status: Abandoned Application
First Claim
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1. An improved process for isolation of withaferin-A from plant materials and products therefrom, said process comprising steps of:

  • (i) extracting the said plant material in an extraction solvent, (ii) defatting the extract, as obtained in step (i), with partitioning with n-hexane followed by chromatographic separation to obtain withanlidal, (iii) portioning out withanolidal aglycones from the withanlidal, as obtained in step (ii), into a chloroform followed by evaporation of said chloroform, and (iv) dissolving extract as obtained in step (iii) in methanol to obtain withaferin-A.

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