Bi-lateral local renal delivery for treating congestive heart failure and for BNP therapy
First Claim
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1. A method comprising:
- locally administering a natriuretic peptide into at least one renal artery of a patient.
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Abstract
The invention relates to systems and methods for local renal delivery of agents to subjects that are at risk for congestive heart failure and other conditions. The invention encompasses devices for renal drug delivery and methods of use.
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Citations
24 Claims
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1. A method comprising:
locally administering a natriuretic peptide into at least one renal artery of a patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method comprising:
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positioning an intravascular catheter through an aorta so that at least one delivery port is positioned in at least one renal artery; and
delivering an active substance through said intravascular catheter to said at least one renal artery;
wherein the catheter comprises a compliant region which accommodates tension or compression resulting from patient movement when the catheter is positioned in the aorta and the delivery port is in the at least one renal artery. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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21. A renal drug delivery catheter, said catheter comprising:
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a catheter body having a proximal end, a distal end, and a drug delivery lumen therethrough; and
a hub on the proximal end adapted to deliver drugs to the drug delivery lumen;
wherein the distal end of the catheter body is adapted to enter a renal artery when the catheter body is located in an adjacent aorta; and
wherein a portion of the catheter body is compliant and configured to accommodate tension or compression resulting from patient movement when the catheter body is in the aortic and the distal end is in the renal artery. - View Dependent Claims (22, 23, 24)
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Specification