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Percutaneous chemical sensor based on fluorescence resonant energy transfer (FRET)

  • US 20050267326A1
  • Filed: 03/24/2005
  • Published: 12/01/2005
  • Est. Priority Date: 10/02/2001
  • Status: Abandoned Application
First Claim
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1. A device for detecting an analyte from within a patient'"'"'s body, comprising:

  • a) an optical fiber having;

    a first end; and

    a second end configured to intermittently connect and disconnect to an analyzer;

    and b) a biosensing material attached to the first end comprising;

    a polymer matrix;

    at least one receptor molecule attached to the polymer matrix and labeled with a first detector molecule; and

    at least one competitive binding molecule attached to the polymer matrix and labeled with a second detector molecule, wherein the at least one receptor molecule is capable of interacting with the at least one attached competitive binding molecule and with at least one analyte from the patient'"'"'s body.

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