Non-invasive measurement of blood glucose using retinal imaging
First Claim
1. An apparatus that determines blood glucose concentration in an individual, the apparatus comprising:
- a light projector adapted to project a first light into retina of an eye of the individual, wherein the light has a light intensity selected to bleach visual pigment in the retina;
a light detector adapted to detect light reflected from the retina; and
a processor with programmed instructions adapted to determine the blood glucose concentration using the rate of bleaching in the retina.
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Accused Products
Abstract
An apparatus carries out measurements of blood glucose in a repeatable, non-invasive manner by measurement of the rate of regeneration of retinal visual pigments, such as cone visual pigments. The rate of regeneration of visual pigments is dependent upon the blood glucose concentration, and by measuring the visual pigment regeneration rate, blood glucose concentration can be accurately determined. This apparatus exposes the retina to light of selected wavelengths in selected distributions and subsequently analyzes the reflection (as color or darkness) from a selected portion of the exposed region of the retina, preferably from the fovea.
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Citations
30 Claims
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1. An apparatus that determines blood glucose concentration in an individual, the apparatus comprising:
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a light projector adapted to project a first light into retina of an eye of the individual, wherein the light has a light intensity selected to bleach visual pigment in the retina;
a light detector adapted to detect light reflected from the retina; and
a processor with programmed instructions adapted to determine the blood glucose concentration using the rate of bleaching in the retina. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method to determine blood glucose concentration in an individual, the method comprising:
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projecting a light into retina of an eye of the individual, wherein the light has a light intensity selected to bleach visual pigment in the retina;
detecting light reflected from the retina; and
determining the blood glucose concentration using the rate of bleaching in the retina. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30)
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Specification