Implantable bioabsorbable valve support frame

• US 20050267560A1
• Filed: 05/23/2005
• Published: 12/01/2005
• Est. Priority Date: 02/03/2000
• Status: Abandoned Application

• Current Assignee: Cook Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Bates, Brian L.
• Application Number:
  US11/136,039
• Publication Number:
  US 20050267560A1
• Time in Patent Office: Days
• US Class Current: 623/1.100
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0023 triangular
• CPC Class Codes: A61F 2230/0026 trapezoidal
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0095 Saddle-shaped

Abstract

Medical devices for implantation within a body vessel comprising a frame formed at least in part from a metallic bioabsorbable material are provided. The devices can be pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material, or a bioabsorbable material, including a collagen-based material such as small intestinal submucosa (SIS), may be attached to the frame to form an occlusion device, a graft, or an implantable, intraluminal valve such as for correcting incompetent venous valves.

Claims

1. A medical device for implantation in a body vessel comprising:

a support frame comprising a metallic bioabsorbable material and at least one leaflet attached to a portion of the support frame.

2. The medical device of claim 1, wherein the metallic bioabsorbable material is selected from a first group consisting of:

magnesium, titanium, zirconium, niobium, tantalum, zinc, silicon and mixtures thereof.

3. The medical device of claim 1, wherein the bioabsorbable material is a bioabsorbable alloy of two or more metals.

4. The medical device of claim 3, wherein the alloy comprises a first metal selected from a first group consisting of:

magnesium, titanium, zirconium, niobium, tantalum, zinc, silicon and mixtures thereof; and

a second metal selected from the group consisting of;

lithium, sodium, potassium, calcium, iron, manganese, and mixtures thereof.

5. The medical device of claim 3, wherein the bioabsorbable alloy is selected from the group consisting of:

lithium-magnesium, sodium-magnesium, zinc-titanium and mixtures thereof.

6. The medical device of claim 3, wherein the bioabsorbable alloy further comprises gold.

7. The medical device of claim 1, where the leaflet comprises a free edge.

8. The medical device of claim 1, where the support frame defines substantially cylindrical lumen.

9. The medical device of claim 8, where the leaflet comprises a free edge that is moveable in response to the flow of fluid through the lumen.

10. The medical device of claim 8, where the leaflet permits fluid to flow through the lumen in a first direction while substantially preventing fluid flow through the lumen in the opposite direction.

11. The medical device of claim 1, comprising two or more leaflets attached to the support frame, wherein each leaflet comprises a remodelable material that is attached to one or more portions of the support frame.

12. The medical device of claim 1, wherein the medical device comprises at least two leaflets.

13. The medical device of claim 12, where the medical device comprises an opposable pair of leaflets and each of the opposable pair of leaflets comprises a flexible free edge, and where each flexible free edge of each leaflet cooperably define at least a portion of a valve orifice.

14. The medical device of claim 1, where the leaflet comprises a polyurethane material and a surface modifying agent.

15. The medical device of claim 1, where the leaflet comprises a remodelable material.

16. The medical device of claim 1, where the leaflet comprises small intestine submucosa.

17. The medical device of claim 1, where the support frame further comprises a means for orienting the support frame in a body vessel.

18. A medical device for implantation in a body vessel comprising:

a support frame comprising a metallic bioabsorbable material and a means for regulating fluid in a body vessel.

19. A method of making a medical device for implantation in a body vessel, comprising the step of attaching a first valve leaflet to a support frame, the support frame comprising a metallic bioabsorbable material and at least one leaflet attached to a portion of the support frame.

20. A method of treating a subject, comprising the step of:

delivering the medical device to a point of treatment in a body vessel;

the medical device comprising a support frame formed at least in part from metallic bioabsorbable material and at least one leaflet attached to a portion of the support frame.