System and method for automated titration of continuous positive airway pressure

• US 20050268912A1
• Filed: 06/04/2004
• Published: 12/08/2005
• Est. Priority Date: 06/04/2004
• Status: Abandoned Application

• Current Assignee: New York University
• Original Assignee: New York University
• Inventors: Norman, Robert G., Rapoport, David M.
• Application Number:
  US10/862,067
• Publication Number:
  US 20050268912A1
• Time in Patent Office: Days
• US Class Current: 128/204.230
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/10 Preparation of respiratory gases or vapours
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit

Abstract

Described is a method and system for automated titration of CPAP. The system may include an air pressure supply providing air pressure to a patient'"'"'s airways and a sensor detecting input data corresponding to a patient'"'"'s breathing patterns of a plurality of breaths. The system also includes a titration device which receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generating output data for adjusting the air pressure supplied to the patient as a function of the characteristics of the breathing disorder.

Claims

1. A system, comprising:

an air pressure supply arrangement providing air pressure to a patient'"'"'s airways;

a sensor detecting input data corresponding to a patient'"'"'s breathing patterns of a plurality of breaths; and

a titration device receiving and analyzing the input data to determine existence of breathing disorder and corresponding characteristics, the titration device generating output data for adjusting the air pressure supplied to the patient as a function of the characteristics of the breathing disorder.

2. The system according to claim 1, wherein the input data is obtained for at least one time period prior to generating the output data.

3. The system according to claim 2, wherein the at least one time period includes a sleep session that starts when the patient falls asleep and ends when the patient is awakened.

4. The system according to claim 2, wherein the at least one time period includes at least one portion of a sleep session, the sleep session starting when the patient falls asleep and ending when the patient is awakened.

5. The system according to claim 2, wherein the pressure supplied to the patient is adjusted as a function of the output data.

6. The system according to claim 1, wherein the titration device is a portable unit which is removably attached to the air pressure supply arrangement.

7. The system according to claim 1, further comprising:

an arrangement covering at least one of a nose and a mouth of the patient.

8. The system according to claim 7, further comprising:

a tube connected to the arrangement, the air pressure supply arrangement providing a flow of air via the tube to the arrangement.

9. The system according to claim 8, further comprising:

a further sensor coupled to the arrangement, the further sensor adapted to provide a portion of the input data to the titration device related the flow of air in the arrangement.

10. The system according to claim 1, further comprising:

a venting arrangement allowing gases exhaled by the patient to be diverted from incoming air.

11. The system according to claim 1, wherein the sensor is external to the air pressure supply arrangement.

12. The system according to claim 1, wherein the sensor is internal to the air pressure supply arrangement.

37. The system according to claim 2, wherein the at least one time period is at least one sleep cycle of a patient.

13. A method, comprising the steps of:

activating a titration device;

obtaining input data by the titration device from a sensor, the input data corresponding to a patient'"'"'s breathing patterns;

determining with the titration device existence in the input data one of a breathing disorder and an abnormal flow limitation and corresponding characteristics; and

generating using the titration device an output data as a function of the characteristics for adjusting the pressure provided to the patient.

14. The method according to claim 13, wherein a currently supplied airflow pressure is utilized to generate the output data.

15. The method according to claim 13, wherein the titration device is activated by one of applying power to the titration device and wherein the method further comprising the step of:

connecting the titration device to a Continuous Positive Airway Pressure System.

16. The method according to claim 13, further comprising the step of:

deactivating the titration device after a predetermined time period.

17. The method according to claim 13, wherein the input data is obtained for at least one time period prior to generating the output data.

18. The method according to claim 13, wherein the at least one time period includes at least one sleep session that starts when the patient falls asleep and ends when the patient is awakened.

19. The method according to claim 18, wherein the at least one time period includes at least one portion of a sleep session, the sleep session starting when the patient falls asleep and ending when the patient is awakened.

20. The method according to claim 18, further comprising the step of:

adjusting the pressure supplies to the patient as a function of the control data.

21. The method according to claim 13, further comprising the step of:

storing the input and output data in a memory arrangement.

22. The method according to claim 21, wherein the memory arrangement is portable and removable from the titration device.

23. The method according to claim 13, wherein the breathing disorder includes one or more of apnea, hypopnea and elevation in a resistance of an upper airway of the patient.

24. The method according to claim 13, wherein the input data is obtained until a predetermined event occurs.

25. The method according to claim 24, wherein the predetermined event includes at least one of an index of breathing disorders and a predetermined deviation value of the breathing disorder as compared a predefined value.

26. The method according to claim 25, further comprising the steps of:

generating the output data to decrease the pressure, when the index of the breathing disorders is lower than a predefined value.

27. The method according to claim 25, further comprising the steps of:

generating the output data to increase the pressure, when the index of the breathing disorders is greater than a predefined value

28. A method, comprising the steps of:

coupling to a positive airway pressure supply system a removable diagnostics unit, the positive airway supply system including a source of positive pressure, an airway for supply of the positive pressure to a patient'"'"'s airway and at least one sensor sensing data corresponding to breathes of the patient, the diagnostics unit including a processor, a memory, an input module receiving input data from the at least one sensor and an output module for outputting control data to the positive airway pressure supply system;

obtaining the input data from the at least one sensor to be stored in the memory;

processing the input data obtained from the at least one sensor using the processor to determine a breathing disorder and corresponding characteristics;

generating the control data for adjusting operation of the positive airway pressure supply system based on the characteristics of the breathing disorder determined by the processor; and

transmitting the control data to the positive airway pressure supply system via the output module.

29. The method according to claim 28, wherein the data is obtained for at least one time period prior to generating the control data.

30. The method according to claim 29, wherein the at least one time period includes at least one sleep session that starts when the patient falls asleep and ends when the patient is awakened.

31. The method according to claim 29, wherein the at least one time period includes at least one portion of a sleep session, the sleep session starting when the patient falls asleep and ending when the patient is awakened.

32. The method according to claim 29, further comprising the step of:

adjusting the pressure supplies to the patient as a function of the control data.

33. A diagnostic device, comprising:

an input module receiving input data from at least one sensor, the input data corresponding to breathing patterns of a patient

a memory storing the input data;

a processor processing the input data to determine a breathing disorder and corresponding characteristics, the processor generating output data for adjusting operation of a positive airway pressure supply system based on the characteristics of the breathing disorder; and

an output module outputting the output data to the system,

wherein the device is a removably coupled the system.

34. The device according to claim 33, wherein the input data is obtained for at least one time period prior to generating the control data.

35. The device according to claim 34, wherein the at least one time period includes at least one sleep session that starts when the patient falls asleep and ends when the patient is awakened.

36. The device according to claim 34, wherein the at least one time period includes at least one portion of a sleep session, the sleep session starting when the patient falls asleep and ending when the patient is awakened

38. A method for titration of an air pressure supplied to a patient'"'"'s airway, comprising the steps of:

(a) obtaining input data by a titration device from a sensor, the input data corresponding to a patient'"'"'s breathing patterns;

(b) determining, with the titration device, existence in the input data of one of (i) a breathing disorder and corresponding characteristics thereof and (ii) an abnormal flow limitation and corresponding characteristics thereof;

(c) generating, using the titration device, output data as a function of the characteristics; and

(d) adjusting the air pressure supplied to the patient'"'"'s airway as a function of the output data.

39. The method according to claim 38, wherein steps (a)-(d) are performed over a first predetermined time period.

40. The method according to claim 39, wherein the first predetermined time period is at least one sleep cycle of the patient, the sleep cycle starts when the patient falls asleep and terminates when the patient is awakened.

41. The method according to claim 38, wherein steps (a)-(d) are repeated over at least one further predetermined time period, the at least one further predetermined time period separated temporally from the first predetermined time period.

42. The method according to claim 41, wherein during the at least one further predetermined time period, further input data is obtained and further output data is generated.

43. The method according to claim 42, wherein a comparison is made of at least one of the further input data and the further output data to at least one of the input data and the output data.

44. The method according to claim 43, wherein the air pressure supplied to the patient is determined as a function of the comparison.