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Methods for identifying risk of breast cancer and treatments thereof

  • US 20050272043A1
  • Filed: 05/27/2004
  • Published: 12/08/2005
  • Est. Priority Date: 07/24/2003
  • Status: Abandoned Application
First Claim
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1. A method for identifying a subject at risk of breast cancer, which comprises detecting the presence or absence of a polymorphic variation associated with breast cancer corresponding to a position selected from the group consisting of rs5030391, rs10402760, rs710845, position 30965 of SEQ ID NO:

  • 2, rs3775168, position 38865 of SEQ ID NO;

    2, position 39035 of SEQ ID NO;

    2, position 39046 of SEQ ID NO;

    2, rs4630966, rs9827084, rs9864865, rs6804951, rs6770548, rs7949480, rs7121260, rs7128317, rs2276385, rs2276383, rs1892921, rs1541306, rs3814721, rs1892919, rs2852365, rs3750913, position 34941 in SEQ ID NO;

    4, rs949325, position 35629 in SEQ ID NO;

    4, rs2298456, rs1573500, rs4945411, rs10128658, rs2298457, rs3838779, rs10898814, rs7930142, rs7930544, rs7930722, rs1939247, rs1939243, rs4245463, rs4944258, rs7926751, rs1573502, rs7127865, rs1894003, rs4945430, rs1939242, rs10793016, rs4945434, rs678193, rs560777, rs676721, rs585228, rs675185, rs5792574, rs2511075, rs541022, rs1791544, rs642618, rs552966, rs607446, rs3018302, rs3018301, rs2511114, rs548961, rs579320, rs495567, rs493065, rs610004, rs610041, rs673478, rs670802, rs2511116, rs615000, rs482013, rs2511079, rs2250866, rs2508858, rs2276396, rs11278712, rs2294495, position 15761 of SEQ ID NO;

    5, rs8179467, rs11591202, rs12034848, rs3831910, rs4237, rs2232982, rs12041159, rs2076343, rs1018396, rs12044452, rs2982390, rs2502980, rs6697805, rs10554242, rs3327, rs2526926, rs2526914, rs2526913, rs2526921, rs7159986, rs2332916, rs10132242, rs11627663, rs4899441, rs7148199, rs1990437, rs8004210, rs8019653, rs12232220, rs4899442, rs2332917, rs8015749, rs12437188, rs12432148, rs4378563, rs740978, rs740976, rs4903059, rs4903060, rs9635259, rs2052142, rs758913, rs747987, rs11423372, rs5809592, rs8007348, rs4899445, rs4903062, rs1990440, rs4479167, rs4606655, rs4606656, rs4489943, rs8007559, rs8006156, rs12431400, rs12431384, rs12433097, rs12433184, rs2877821, rs4569195, rs11628905, rs2191822, rs12433603, rs11448438, rs8009692, rs4265749, rs4307892, rs12431975, rs4903071, rs1860749, rs1860748, rs8010957, rs6420906, rs12434800, rs7142579, rs8010875, rs8004767, rs4899449, rs10605948, rs12437080, rs12431943, rs1054745, rs8019453, rs12431547, rs1959029, rs1959028, rs8013347, rs2235972, rs2235973, rs2235974, and rs2895908;

    whereby the presence of the one or more polymorphic variations associated with breast cancer is indicative of the subject being at risk of breast cancer.

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