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Analyte sensors and methods for making and using them

  • US 20050272989A1
  • Filed: 06/04/2004
  • Published: 12/08/2005
  • Est. Priority Date: 06/04/2004
  • Status: Abandoned Application
First Claim
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1. An analyte sensor apparatus for implantation within a mammal, the analyte sensor apparatus comprising:

  • a base layer;

    a conductive layer disposed upon the base layer wherein the conductive layer includes a working electrode;

    an analyte sensing layer disposed on the conductive layer, wherein the analyte sensing layer detectably alters the electrical current at the working electrode in the conductive layer in the presence of an analyte;

    an adhesion promoting layer disposed on the analyte sensing layer, wherein the adhesion promoting layer promotes the adhesion between the analyte sensing layer and an analyte modulating layer disposed on the analyte sensing layer; and

    an analyte modulating layer disposed on the analyte sensing layer, wherein the analyte modulating layer modulates the diffusion of the analyte therethrough; and

    wherein;

    the analyte sensor apparatus is structured to function via anodic polarization such that the alteration in current can be detected at the anode working electrode in the conductive layer of the analyte sensor apparatus; and

    the alteration in current that can be detected at the anode working electrode can be correlated with the concentration of the analyte.

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