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Method for delivering drugs to the adventitia using device having microprojections

  • US 20050273075A1
  • Filed: 06/08/2004
  • Published: 12/08/2005
  • Est. Priority Date: 06/08/2004
  • Status: Abandoned Application
First Claim
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1. A method for delivering a therapeutic agent into tissue, the method comprising the steps of:

  • providing a device for delivering a therapeutic agent into tissue, the device comprising;

    an elongated body;

    a first balloon in the body expandable from a collapsed position to an expanded position;

    a second balloon in the body expandable from a collapsed position to an expanded position, the second balloon having a plurality of apertures therein;

    a therapeutic agent in the second balloon; and

    a plurality of microprojections on a surface of the second balloon for penetrating tissue; and

    wherein upon expansion of the first balloon from the collapsed position to the expanded position, the second balloon is expanded from the collapsed position to the expanded position for deploying the plurality of microprojections into tissue and for dispensing the therapeutic agent from the second balloon into the tissue through the plurality of apertures;

    placing the device adjacent a site in the tissue; and

    delivering the therapeutic agent into the tissue at the site by expanding the first balloon from the collapsed position to the expanded position.

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