Load bearing biocompatible device
First Claim
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1. An implantable hydrogel substrate comprising a hydrogel surface having a plurality of superficial pores thereon.
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Abstract
Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
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Citations
24 Claims
- 1. An implantable hydrogel substrate comprising a hydrogel surface having a plurality of superficial pores thereon.
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15. A method of making a hydrogel substrate comprising:
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a. contacting solid objects with a liquid hydrogel, b. allowing the aqueous hydrogel to polymerize and crosslink while the solid objects are at least partially immersed in the surface region of the hydrogel, and c. removing said solid objects from the polymerized and crosslinked hydrogel to form superficial pores thereon. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification