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Cardiac conduction system cells and uses thereof

  • US 20050277124A1
  • Filed: 10/07/2004
  • Published: 12/15/2005
  • Est. Priority Date: 06/10/2004
  • Status: Abandoned Application
First Claim
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1. A method of identifying a population of non-contracting cardiac pacemaking cells comprising:

  • transfecting a stem cell with an expression construct comprising a GATA-6 regulatory element operably linked to a coding sequence for a surrogate marker, wherein the promoter element is selectively active in cardiomyocytes that display an If pacemaking current.

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