Method for carrying out a biochemical protocol in continuous flow in a microreactor
First Claim
1. A method of performing a chemical or biochemical protocol comprising:
- cycling at least one thermal transfer member between at least two temperatures while liquid samples on which said chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which said at least one thermal transfer member acts.
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Accused Products
Abstract
Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.
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Citations
27 Claims
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1. A method of performing a chemical or biochemical protocol comprising:
- cycling at least one thermal transfer member between at least two temperatures while liquid samples on which said chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which said at least one thermal transfer member acts.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for carrying out a chemical or biochemical protocol comprising:
- depositing liquid sample volumes into a plurality of sample receiving regions on at least one mobile sample transport member; and
moving the sample transport member along a pathway such that said sample receiving regions move through at least one temperature regulated zone upon which a thermal transfer member acts, wherein said thermal transfer member is capable of cycling between at least two temperatures while said sample receiving regions are moving through said at least one temperature regulated zone.
- depositing liquid sample volumes into a plurality of sample receiving regions on at least one mobile sample transport member; and
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10. A device comprising:
- a substrate comprising regions for receiving liquid samples wherein said liquid samples move along at least one sample pathway; and
at least one thermal transfer member which is capable of cycling between at least two temperatures, said at least one thermal transfer member being adapted to bring at least a portion of said sample pathway to said at least two temperatures while a sample is continuously moving along said at least a portion of said sample pathway. - View Dependent Claims (11, 12, 13)
- a substrate comprising regions for receiving liquid samples wherein said liquid samples move along at least one sample pathway; and
- 14. A device comprising at least one mobile sample transport member having sample receiving regions thereon and at least one thermal transfer member which is capable of cycling between at least two temperatures, said at least one thermal transfer member being adapted to allow said sample receiving regions to cycle between at least two temperatures while said sample receiving regions are moving through at least one temperature regulated zone upon which said at least one thermal transfer member acts.
Specification