Cross-linked gel and pressure sensitive adhesive blend, and skin-attachable products using the same

• US 20050282977A1
• Filed: 06/17/2004
• Published: 12/22/2005
• Est. Priority Date: 06/17/2004
• Status: Abandoned Application

• Current Assignee: Hollister Incorporated
• Original Assignee: Hollister Incorporated
• Inventors: Stempel, Emil, Leung, Pak-Tong
• Application Number:
  US10/870,883
• Publication Number:
  US 20050282977A1
• Time in Patent Office: Days
• US Class Current: 525/477
• CPC Class Codes: A61L 15/585 Mixtures of macromolecular compounds
• CPC Class Codes: C08G 77/12 containing silicon bound to hydrogen C08G77/045 takes precedence
• CPC Class Codes: C08G 77/16 to hydroxyl groups
• CPC Class Codes: C08G 77/20 containing silicon bound to unsaturated aliphatic groups C08G77/045 takes precedence
• CPC Class Codes: C08G 77/44 containing only polysiloxane sequences
• CPC Class Codes: C08L 83/00 Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: Y10T 428/31663 As siloxane, silicone or silane

Abstract

A pressure sensitive adhesive composition comprising a compatible blend of (1) a gel preferably comprising a copolymer of an organosiloxane and a siloxane having a plurality of reactive functionalities reacted with a cross-liking agent; and (2) a pressure sensitive adhesive that preferably is essentially non-reactive with the reactive functionalities of said copolymer gel or the copolymer cross-liking agent of said gel, wherein the essentially non-reactive pressure sensitive adhesive is a silicone pressure sensitive adhesive and has a higher adhesive strength than said gel and is blended with said copolymer during cross-linking of said copolymer to form said gel.

Claims

1. A pressure sensitive adhesive composition comprising a compatible blend of (1) a cross-linked adhesive gel and (2) a pressure sensitive adhesive, wherein the pressure sensitive adhesive has a higher adhesive strength than said gel, and is blended with the gel during the cross-linking to form said gel.

2. The pressure sensitive adhesive composition of claim 1, comprising 40 wt. %-90 wt. % (1) and 10 wt. %-60 wt. % (2).

3. The pressure sensitive adhesive composition of claim 1, wherein the composition includes sufficient organic liquid to swell the adhesive gel.

47. A method of adhering a device to human skin comprising coating at least a portion of the device, or a tape used to secure the device, with the composition of claim 1, and then contacting the coating against the skin.

49. The method of claim 47, wherein the device is selected from the group consisting of an ostomy appliance, a patient monitoring device, a prosthetic device, a hairpiece, medical tape, a skin barrier sheet, a skin barrier ring, a male external catheter, a retracted penis pouch, a female continence device, a fecal pouch, a glans cap, a wound care dressing, a bandage, a burn dressing, surgical tape, ankle support tape, hand support tape, a transdermal drug delivery patch, scar therapy dressing, an island dressing, a reclosable wound cover, a foam dressing, tape to secure an I.V. needle, tape to secure a catheter, and means for securing a device to a breast.

4. A pressure sensitive adhesive composition comprising a compatible blend of (1) a cross-linked silicone gel comprising an organopolysiloxane reacted with a cross-liking agent;

and (2) a silicone pressure sensitive adhesive, wherein the silicone pressure sensitive adhesive has a higher adhesive strength than said gel and is blended with said gel during the cross-linking to form said gel.

5. The pressure sensitive adhesive composition of claim 4, wherein the composition includes sufficient organic liquid to swell the silicone gel.

6. The pressure sensitive adhesive composition of claim 4, wherein the gel is a copolymer of a diorganosiloxane and an alkenyl siloxane.

7. The pressure sensitive adhesive composition of claim 6, wherein the diorganosiloxane is dimethylsiloxane, and the alkenyl siloxane comprises a vinyl siloxane.

8. The pressure sensitive adhesive composition of claim 4, wherein the gel is a copolymer of an organosiloxane and a siloxane having a plurality of reactive sites cross-linked with a hydrosilation agent.

9. The pressure sensitive adhesive composition of claim 8, wherein the hydrosilation agent is methylhydrogen siloxane.

10. The pressure sensitive adhesive composition of claim 8, wherein the cross-linking agent is a polymethylhydrogen siloxane fluid.

11. The pressure sensitive adhesive composition of claim 10, wherein the cross-linking agent is a trimethyl chainstopped polymethylhydrogen siloxane fluid having at least about 10% SiH groups.

12. The pressure sensitive adhesive composition of claim 4, wherein the essentially non-reactive silicone pressure sensitive adhesive (2) is essentially non-reactive with the organopolysiloxane of said gel or with the cross-linking agent of said gel and is a pre-reacted, condensation reaction product of an organopolysiloxane resin having a plurality of reactive moieties, and an organopolysiloxane having a reactive functional group that is reactive with a reactive moiety of said resin.

13. The pressure sensitive adhesive composition of claim 12, wherein the essentially non-reactive silicone pressure sensitive adhesive (2) comprises a reaction product of an organopolysiloxane resin containing silicon-bonded hydroxyl moieties, and the organopolysiloxane reacted with the resin contains a silicon-bonded hydroxyl reactive group.

14. The pressure sensitive adhesive composition of claim 13, wherein the organopolysiloxane resin is a polydimethylsiloxane containing about 1% to about 7% by weight hydroxyl functionalities, based on the weight of resin solids;

and the organopolysiloxane reacted with the resin comprises a dimethylpolysiloxane containing a plurality of hydroxyl groups.

15. The pressure sensitive adhesive compositions of claim 14, wherein the dimethylpolysiloxane that is condensation reacted with the resin is silanol end-blocked and comprises at least 50 wt. % solids in an organic solvent.

16. The pressure sensitive adhesive composition of claim 12, wherein the organopolysiloxane reacted with the resin is end-blocked with a reactive group selected from the group consisting of silanol, and alkenyl.

17. The pressure sensitive adhesive composition of claim 16, wherein the organopolysiloxane, reacted with the resin, is vinyl end-capped.

18. The pressure sensitive adhesive composition of claim 4, containing 0.5% to 99.5% by weight of (1) and 99.5% to 0.5% of (2), based on the total weight of silicone pressure sensitive adhesive solids in the composition.

19. The pressure sensitive adhesive composition of claim 18, containing 40 wt. %-90 wt. % (1) and 10-60 wt. % (2).

23. A collection pouch to be adhesively secured to a wearer'"'"'s skin for collecting waste discharged through a natural or surgically-formed orifice;

said pouch having side walls of liquid- and gas-impermeable flexible polymeric film with one of said walls being provided with an opening for receiving body waste; and

attachment means attached to said pouch about said opening for removably attaching said pouch to a wearer'"'"'s skin;

said means comprising the pressure sensitive adhesive composition of claim 4.

24. The collection pouch of claim 23 in which said gel constitutes about 40 to 90% by weight of said blend.

25. The collection pouch of claim 24 in which said gel constitutes about 50 to 80% by weight of said blend.

48. A method of adhering a device to human skin comprising coating at least a portion of the device, or a tape used to secure the device, with the composition of claim 4, and then contacting the coating against the skin.

50. The method of claim 48, wherein the device is selected from the group consisting of an ostomy appliance, a patient monitoring device, a prosthetic device, a hairpiece, medical tape, a skin barrier sheet, a skin barrier ring, a male external catheter, a retracted penis pouch, a female continence device, a fecal pouch, a glans cap, a wound care dressing, a bandage, a burn dressing, surgical tape, ankle support tape, hand support tape, a transdermal drug delivery patch, scar therapy dressing, an island dressing, a reclosable wound cover, a foam dressing, tape to secure an I.V. needle, tape to secure a catheter, and means for securing a device to a breast.

20. A soft tacky skinfriendly sealant for removably securing body waste collectors and other objects to a wearer'"'"'s skin, consisting essentially of a blend of a hypoallergenic silicone pressure sensitive adhesive and a compatible silicone gel;

said silicone gel comprising a lightly cross-linked addition-polymerization reaction product of a poly(dimethylsiloxane-co-vinylsiloxane) and a methylhydrogen siloxane, with said gel constituting 0.5% to 99.5% by weight of said blend.

21. The sealant of claim 20 in which said gel constitutes about 40 to 90% by weight of said blend.

22. The sealant of claim 21 in which said gel constitutes about 50 to 80% by weight of said blend.

26. A method of increasing the adhesive strength of a cross-linked gel during manufacture of said gel comprising blending a pressure sensitive adhesive, having more adhesive strength than the adhesive strength of the gel, with said gel during a cross-linking reaction used to form said gel.

28. The method of claim 26, further including the step of shearing the blend sufficiently to form a homogeneous composition.

30. The method of claim 26, wherein the blended adhesives include sufficient organic liquid to swell the cross-linked gel.

31. The method of claim 30, wherein the gel is a cross-linked copolymer of a diorganosiloxane and an alkenyl siloxane.

32. The method of claim 31, wherein the alkenyl siloxane comprises a vinyl siloxane.

33. The method of claim 26, wherein the gel is cross-linked with a hydrosilation agent.

34. The method of claim 33, wherein the hydrosilation agent is a methylhydrogen siloxane.

35. The method of claim 34, wherein the hydrosilation agent is a polymethylhydrogen siloxane fluid.

36. The method of claim 35, wherein the cross-linking agent is a trimethyl chainstopped polymethylhydrogen siloxane fluid having at least about 10% SiH groups.

37. The method of claim 26, wherein the silicone pressure sensitive adhesive blended with the gel is essentially non-reactive with the cross-linking agent used to form said gel.

38. The method of claim 37, wherein the silicone pressure sensitive adhesive blended with the gel is a pre-reacted, condensation reaction product of an organopolysiloxane resin and an organopolysiloxane fluid.

39. The method of claim 38, wherein the essentially non-reactive silicone pressure sensitive adhesive (2) comprises a reaction product of an organopolysiloxane resin containing silicon-bonded hydroxyl moieties, and the organopolysiloxane reacted with the resin contains a silicon-bonded hydroxyl reactive group.

40. The method of claim 39, wherein the organopolysiloxane resin is a polydimethylsiloxane containing about 1% to about 7% by weight hydroxyl functionalities, based on the weight of resin solids;

and the organopolysiloxane reacted with the resin comprises a dimethylpolysiloxane containing a plurality of hydroxyl groups.

41. The method of claim 38, wherein the dimethylpolysiloxane that is condensation reacted with the resin is silanol end-blocked and the cross-linked PSA gel comprises at least 50 wt. % solids in an organic solvent.

42. The method of claim 38, wherein the organopolysiloxane reacted with the resin is end-blocked with a reactive group selected from the group consisting of silanol, and alkenyl.

43. The method of claim 42, wherein the organopolysiloxane, reacted with the resin, is vinyl end-capped.

44. The method of claim 26, wherein the amount of silicone pressure sensitive adhesive blended with the gel, during cross-linking of the gel, comprises 0.5 wt. % to 99.5%, based on the total weight of gel and blended silicone pressure sensitive adhesive.

45. The method of claim 44, wherein the blend comprises 40 wt. % to 95 wt. % gel and 60 wt. % to 5 wt. % blended silicone pressure sensitive adhesive.

46. The method of claim 45 wherein the blend comprises 70 wt. % to 90 wt. % gel and 30 wt. % to 10 wt. % blended silicone pressure sensitive adhesive.

27. A method of increasing the adhesive strength of a lightly cross-linked silicone gel during manufacture of said gel comprising blending a silicone pressure sensitive adhesive, having more adhesive strength than the adhesive strength of the gel, with said gel during a cross-linking reaction used to form said gel.

29. The method of claim 27, further including the step of shearing the blend sufficiently to form a homogeneous composition.