Hollow fiber contactor systems for removal of lipids from fluids
First Claim
1. A device for removing at least one lipid from a fluid containing lipids or from a lipid-containing organism, comprising:
- at least one hollow fiber contactor for;
contacting the fluid containing lipids with a first extraction solvent in the at least one hollow fiber contactor and forming a first mixture comprising the fluid and the first extraction solvent, wherein at least a portion of the lipids dissolve in the first extraction solvent;
removing at least a portion of the first extraction solvent from the first mixture by contacting the first mixture with a second extraction solvent in the at least one hollow fiber contactor, which forms a second mixture comprising the first extraction solvent, the second extraction solvent and the fluid; and
removing at least a portion of the second extraction solvent from the second mixture.
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Accused Products
Abstract
This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.
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Citations
17 Claims
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1. A device for removing at least one lipid from a fluid containing lipids or from a lipid-containing organism, comprising:
at least one hollow fiber contactor for;
contacting the fluid containing lipids with a first extraction solvent in the at least one hollow fiber contactor and forming a first mixture comprising the fluid and the first extraction solvent, wherein at least a portion of the lipids dissolve in the first extraction solvent;
removing at least a portion of the first extraction solvent from the first mixture by contacting the first mixture with a second extraction solvent in the at least one hollow fiber contactor, which forms a second mixture comprising the first extraction solvent, the second extraction solvent and the fluid; and
removing at least a portion of the second extraction solvent from the second mixture. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for removing at least one lipid from a fluid containing lipids or from a lipid-containing organism, comprising:
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contacting the fluid with a first extraction solvent in at least one hollow fiber contactor and forming a first mixture comprising the fluid and the first extraction solvent, wherein at least a portion of the lipids dissolve in the first extraction solvent;
removing at least a portion of the first extraction solvent from the first mixture by contacting the first mixture with a second extraction solvent in the at least one hollow fiber contactor, which forms a second mixture comprising the first extraction solvent, the second extraction solvent and the fluid; and
removing at least a portion of the second extraction solvent from the second mixture using the at least one hollow fiber contactor.
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Specification