Method and system for the prediction of cardiac arrhythmias
First Claim
1. A method for determining an increased likelihood of the occurrence of a cardiac arrhythmia in a patient, the method comprising:
- monitoring the sympathetic neural discharges of the patient from the left stellate ganglion or the thoracic ganglia; and
detecting an increase in the sympathetic neural discharges.
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Abstract
Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a patient from the left stellate ganglion, the thoracic ganglia, or both, and detecting increases in the sympathetic neural discharges. The methods and systems may further comprise delivering anti-arrhythmic therapy to the patient in response to a detected increase in the sympathetic neural discharge, such as delivering one or more pharmacological agents; stimulating myocardial hyperinnervation in the sinus node and right ventricle of the heart of the patient; and applying cardiac pacing, cardioversion or defibrillation shocks. Pharmacologic agents which may be used in connection with the delivery of anti-arrhythmic therapy include those which are known to exert anti-arrhythmic effect and anti-convulsant agents, such as phenyloin, carbamazepine, valproate, and phenobarbitone.
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Citations
28 Claims
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1. A method for determining an increased likelihood of the occurrence of a cardiac arrhythmia in a patient, the method comprising:
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monitoring the sympathetic neural discharges of the patient from the left stellate ganglion or the thoracic ganglia; and
detecting an increase in the sympathetic neural discharges. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A system for determining an increased likelihood of the occurrence of a cardiac arrhythmia in a patient, the system comprising:
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a sensor for acquiring data relating to the sympathetic neural discharges of a patient from the left stellate ganglion or the thoracic ganglia;
a processor for receiving the data acquired from the sensor, wherein the processor analyzes the data and determines if there is an increase in the sympathetic neural discharge; and
an output unit for generating an output signal in response to a determined increase in the sympathetic neural discharge. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. A cardiac arrhythmia prediction system comprising:
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means for monitoring the sympathetic neural discharges of a patient from the left stellate ganglion or the thoracic ganglia;
means for determining an increase in the sympathetic neural discharge; and
means for producing an output signal in response to a determined increase in the sympathetic neural discharge. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28)
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Specification