Product

• US 20060008505A1
• Filed: 07/08/2005
• Published: 01/12/2006
• Est. Priority Date: 07/08/2004
• Status: Abandoned Application

• Current Assignee: Alltracel Development Services Limited, Biofilm Incorporated
• Original Assignee: Alltracel Development Services Limited, Biofilm Incorporated
• Inventors: Brandon, Gerard J.
• Application Number:
  US11/176,580
• Publication Number:
  US 20060008505A1
• Time in Patent Office: Days
• US Class Current: 424/426
• CPC Class Codes: A61F 13/0233 characterised by the oclusive layer skin contacting layer
• CPC Class Codes: A61F 13/0253 characterized by the adhesive material
• CPC Class Codes: A61F 2013/00472 with chemical means
• CPC Class Codes: A61K 31/716 Glucans
• CPC Class Codes: A61L 15/28 Polysaccharides or their derivatives A61L15/225 takes precedence
• CPC Class Codes: A61L 15/58 Adhesives
• CPC Class Codes: A61L 15/64 specially adapted to be resorbable inside the body
• CPC Class Codes: C08L 1/02 Cellulose; Modified cellulose
• CPC Class Codes: C08L 1/04 Oxycellulose; Hydrocellulose , e.g. microcrystalline cellulose
• CPC Class Codes: C08L 5/06 Pectin; Derivatives thereof

Abstract

A delivery system for a haemostatic material comprises a self adhesive strip of a bioadhesive, especially pectin and a glycerol plasticiser. The haemostatic material may be a microdispersed oxidised cellulose which is dispersed in the strip. The strip is applied to control localised bleeding from surface skin wounds such as shaving nicks or minor cuts. The pectin dissolves in the blood, releasing the haemostatic material to control the bleeding.

Claims

1. A delivery system comprising:

a strip of a carrier that is at least partially soluble in blood; and

a haemostatic material that is released as the material of the strip dissolves.

2. A system as claimed in claim 1 wherein the carrier comprises a bioadhesive.

3. A system as claimed in claim 2 wherein the bioadhesive is self adhesive.

4. A system as claimed in claim 1 wherein the carrier comprises pectin.

5. A system as claimed in claim 1 wherein the carrier comprises a plasticiser.

6. A system as claimed in claim 5 wherein the plasticiser comprises glycerine.

7. A system as claimed in claim 1 wherein the haemostatic material is a cellulose based material.

8. A system as claimed in claim 7 wherein the cellulose material is oxidised cellulose.

9. A system as claim in claim 1 wherein the haemostatic material is microdispersed oxidised cellulose.

10. A system as claim in claim 1 wherein the carrier comprises pectin in an amount of at least 30% by weight of the system.

11. A system as claimed in claim 10 wherein the pectin is present in an amount of at least 40% by weight of the system.

12. A system as claimed in claim 10 wherein the pectin is present in an amount of at least 50% by weight of the system.

13. A system as claimed in claim 10 wherein the pectin is present in an amount of approximately 58% by weight of the system.

14. A system as claimed in claim 6 wherein the glycerine is present in an amount of at least 20% by weight of the system.

15. A system as claimed in claim 14 wherein the glycerine is present in an amount of at least 25% by weight of the system.

16. A system as claimed in claim 14 wherein the glycerine is present in an amount of approximately 30% by weight of the system.

17. A system as claimed in claim 9 wherein the microdispersed oxidised cellulose is present in an amount of at least 5% by weight of the system.

18. A system as claimed in claim 17 wherein the microdispersed oxidised cellulose is present in an amount of from 10 to 15% by weight of the system.

19. A system as claimed in claim 17 wherein the microdispersed oxidised cellulose is present in an amount of from 24 to 30% by weight of the system.

20. A system as claimed in claim 1 comprising a preservative such as potassium sorbate.

21. A system as claimed in claim 1 wherein the strip has a thickness of less than 100 microns.

22. A system as claimed in claim 1 wherein the strip has a thickness of from 58 to 70 microns.