Apparatus and method for assessing peripheral circulation to evaluate a physiological condition

• US 20060009700A1
• Filed: 06/08/2005
• Published: 01/12/2006
• Est. Priority Date: 06/08/2004
• Status: Abandoned Application

• Current Assignee: The Government of United States of America As Represented By The Secretary of The Department of Health And Human Services, Centers For Disease Control And Prevention
• Original Assignee: United States Department Of Health And Human Services
• Inventors: Brumfield, Anne M., Andrew, Michael E., Schopper, Aaron W.
• Application Number:
  US11/148,962
• Publication Number:
  US 20060009700A1
• Time in Patent Office: Days
• US Class Current: 600/504
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips

Abstract

Peripheral blood flow signals of a feature can be acquired and analyzed to determine blood flow characteristics for evaluating a physiological condition. Paradigmatic characteristics of blood flow of the feature can be used to associate a physiological condition with a subject. Upon determination that a blood flow characteristic is associated with a physiological condition, action can be taken. For example, the physiological condition can be monitored and given early treatment.

Claims

1. An apparatus for evaluating blood flow within a digit of a subject, said apparatus comprising:

an image-capturing device that is operable to acquire digital representations of the blood flow within said digit; and

a processor configured to receive digital representations from the image-capturing device and generate a signal that is representative of blood flow, wherein the signal can be used to determine a physiological condition of a subject.

2. An apparatus according to claim 1, wherein the image-capturing device comprises a camera.

3. An apparatus according to claim 1, further comprising a force applicator that is adapted to apply a force to said digit.

4. An apparatus according to claim 3, wherein the force applicator comprises a linear stepper motor that increases and decreases the force applied to the digit.

5. An apparatus according to claim 4, wherein the force applicator further comprises a transparent pressing surface;

and

wherein the linear stepper motor is coupled to the pressing surface and operable to cause the pressing surface to press against the digit and move away from the digit so as to increase and decrease the force applied to the digit; and

wherein the image-capturing device is positioned to capture images of the blood flow through the transparent pressing surface

6. An apparatus according to claim 1, further comprising a digit-engagable surface that is adapted to receive a digit, wherein the user presses against the digit-engagable surface to apply a force to said digit.

7. An apparatus according to claim 2, further comprising a focus wheel coupled to the camera.

8. An apparatus according to claim 1, further comprising a photoplethysmograph detector for detecting a photoplethysmograph signal of the digit.

9. An apparatus according to claim 8, further comprising a digit engagable surface that is adapted to receive a digit, and wherein the photoplethysmograph detector is located on the opposite side of the surface from the finger, and the digit-engagable surface is transparent to light detected by the photoplethysmograph detector.

10. One or more computer readable media comprising computer-readable instructions for performing:

receiving a plurality of digital representations of blood flow within a feature over time;

analyzing the digital representations to determine a signal representative of the blood flow.

11-23. -23. (canceled)

24. An apparatus for evaluating blood flow within a digit of a subject, said apparatus comprising:

a force measuring device for measuring force applied to the digit;

a blood flow detector for generating a blood flow signal representative of blood flow in the digit; and

a signal processor configured to;

receive signals from the force measuring device and the blood flow detector;

generate at least one blood flow characteristic based on at least one of;

the signal from the blood flow detector and the signal from the force measuring device;

the signal from the blood flow detector;

or

the signal from the force measuring device;

evaluate at least one physiological condition of the subject based on the at least one blood flow characteristic.

25. An apparatus according to claim 24, wherein the force measuring device is a load cell.

26. An apparatus according to claim 24, wherein the blood flow detector is a photoplethysmograph detector.

27. An apparatus according to claim 26, wherein the photoplethysmograph detector is a photoplethysmograph transducer.

28. An apparatus according to claim 24, wherein the blood flow detector comprises:

an image-capturing device operable to acquire digital representations of the blood flow in the digit; and

a digital representation processor configured to receive digital representations from the image-capturing device and generate said blood flow signal from said digital representations, wherein the signal processor receives said blood flow signal from the digital representation processor.

29. An apparatus according to claim 24, further comprising a digit-engagable surface adapted to receive the digit, and wherein the force measuring device measures the force applied by the digit to the digit-engagable surface.

30. An apparatus according to claim 29, wherein the blood flow detector is a photoplethysmograph detector that is located below the digit-engagable surface, and wherein the digit-engagable surface is transparent to light detected by the photoplethysmograph detector.

31. An apparatus according to claim 29, further comprising a pivotable lever, and wherein said digit-engagable surface is a surface of the pivotable lever.

32. An apparatus according to claim 29, wherein the force measuring device is a load cell located to receive the force applied to the digit-engagable surface.

33. An apparatus according to claim 29, further comprising:

a movable pressing surface; and

a motor coupled to the pressing surface and operable to cause the pressing surface to press the digit against the digit-engagable surface so as to apply the force and to move away from the digit so as to reduce the force.

34. An apparatus according to claim 33, further comprising:

a safety mechanism operable to prevent the application of excessive force to the digit if the force applied by the pressing surface exceeds a predetermined threshold.

35. An apparatus according to claim 33, wherein the blood flow detector comprises:

an image-capturing device that is operable to acquire digital representations of the blood flow within said digit; and

a digital representation processor configured to receive digital representations from the image-capturing device and generate said blood flow signal, wherein the signal processor receives said blood flow signal from the digital representation processor; and

wherein the pressing surface is transparent to allow the image-capturing device to capture images of the blood flow through the pressing surface.

36. An apparatus according to claim 24, wherein the at least one characteristic comprises at least one characteristic selected from the group consisting of:

a rate of return of blood flow within the digit;

a difference between blood flow before the force is applied and blood flow after reducing the force; and

a time interval representative of blood volume return.

37. An apparatus according to claim 24, wherein the signal processor is configured to determine at least one physiological condition based on the at least one blood flow characteristic.

38. An apparatus according to claim 37, wherein the physiological condition is handedness.

39. An apparatus according to claim 37, wherein the physiological condition is age.

40. An apparatus according to claim 37, wherein the physiological condition is a condition demonstrating critical changes in peripheral circulation.

41. An apparatus according to claim 40, wherein the physiological condition is hand arm vibration syndrome (HAVS).

42. An apparatus according to claim 40, wherein the physiological condition is peripheral vascular disease.

43. A method for evaluating blood flow within a feature of a subject, the method comprising:

applying a force to the feature so as to cause a change in the blood flow of the digit;

measuring blood flow within the feature;

determining at least one blood flow characteristic from the measured blood flow corresponding to the change in blood flow; and

analyzing the at least one characteristic to evaluate a physiological condition of the subject.

44-79. -79. (canceled)

80. One or more computer-readable media comprising computer-executable instructions for performing:

receiving a photoplethysmograph signal from a subject;

determining the stability of the signal; and

using the signal for analysis in evaluating a physiological condition of a subject if the stability of the signal is acceptable.

81-92. -92. (canceled)

93. One or more computer-readable media comprising computer executable instructions for performing:

receiving a photoplethysmograph signal from a resting subject;

determining a mean pulse of the signal based on linear associations between pulses within the signal; and

based on at least the mean pulse of the signal, evaluating a physiological condition of a subject.

94-102. -102. (canceled)

103. A system for evaluating a physiological condition of a subject, the system comprising:

means for applying a force to a digit of the subject so as to cause a change in the blood flow of the digit;

means for measuring blood flow within the digit;

means for calculating one or more characteristics of the measured blood flow corresponding to the change in blood flow;

means for evaluating a physiological condition of a subject based at least on the one or more characteristics.

104-105. -105. (canceled)