Graft, stent graft and method

• US 20060009835A1
• Filed: 07/07/2005
• Published: 01/12/2006
• Est. Priority Date: 07/07/2004
• Status: Abandoned Application

• Current Assignee: Cook Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Osborne, Thomas A., Kuppurathanam, Shyam S.V.
• Application Number:
  US11/176,570
• Publication Number:
  US 20060009835A1
• Time in Patent Office: Days
• US Class Current: 623/1.130
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body

Abstract

The invention is directed to grafts, including graft fabrics, for implanting, transplanting, replacing or repairing a part of a patient. The present invention is also directed to stent grafts and endoluminal prostheses formed of the graft fabric. The problem of treating small and tortuous vessels of a patient with stent grafts is solved by providing a graft fabric comprising a plurality of yarns, the yarns having a low denier, wherein the graft and endoluminal prostheses comprising graft fabric can be packable in a delivery system having an outer diameter of from about 0.06 inches to 0.27 inches.

Claims

1. A graft comprising a graft fabric comprising a plurality of yarns, the yarns having a denier of 5 to 50, said graft being packable in an endovascular delivery system having an outer diameter of from about 0.06 inches to about 0.27 inches.

2. The graft of claim 1, wherein the graft is packable in an endovascular delivery system having an outer diameter of from about 0.10 inches to about 0.22 inches.

3. The graft of claim 1, wherein the graft is packable in an endovascular delivery system having an outer diameter of from about 0.13 inches to about 0.19 inches.

4. The graft of claim 1, wherein the yarns are woven or non-woven.

5. The graft of claim 1, wherein the yarns have a denier of 20 to 40.

6. The graft of claim 1, wherein the yarns are made from filaments or fibers having a denier less than or equal to about 1.4.

7. The graft of claim 1, wherein the yarns are made from filaments or fibers having a denier less than or equal to about 0.7.

8. The graft of claim 1, wherein the yarns are made from filaments or fibers having a denier less than or equal to about 0.4.

9. The graft of claim 1, wherein the yarns comprise a synthetic polymer selected from the group consisting of polyester, polypropylene, polyurethane and polytetrafluoroethylene.

10. The graft of claim 1, wherein the graft fabric further comprises a hydrophilic material.

11. The graft of claim 10, wherein the hydrophilic material is mechanically bonded to a surface of the graft fabric.

12. The graft of claim 10, wherein the hydrophilic material is covalently bonded to a surface of the graft fabric.

13. The graft of claim 1, wherein the graft fabric further comprises a bioactive agent.

14. A graft comprising

a graft fabric comprising a plurality of yarns, the yarns having a denier of 5 to 50, the yarns being made from filaments or fibers having a denier less than or equal to about 1.4 and comprising a synthetic polymer;

and

a hydrophilic material,

said graft being packable in an endovascular delivery system having an outer diameter of from about 0.06 inches to about 0.27 inches.

15. An endoluminal prosthesis, comprising

a tubular graft comprising a graft fabric comprising a plurality of yarns, the yarns having a denier of 5 to 50;

and

a stent supporting the graft fabric,

wherein the endoluminal prosthesis is packable in an endovascular delivery system having an outer diameter of from about 0.06 inches to about 0.27 inches.

16. The endoluminal prosthesis of claim 15, wherein the yarns are woven or non-woven.

17. The endoluminal prosthesis of claim 15, wherein the yarns have a denier of 20 to 40.

18. The endoluminal prosthesis of claim 15, wherein the yarns are made from filaments or fibers having a denier less than or equal to about 1.4.

19. The endoluminal prosthesis of claim 15, wherein the graft fabric further comprises hydrophilic material.

20. An endoluminal prosthesis, comprising

a tubular graft, comprising a graft fabric comprising

a plurality of yarns, the yarns having a denier of 5 to 50, the yarns being made from filaments or fibers having a denier less than or equal to about 1.4, and comprising a synthetic polymer, and

a hydrophilic material;

and

a stent supporting the graft fabric,

wherein the endoluminal prosthesis is packable in an endovascular delivery system having an outer diameter of from about 0.06 inches to about 0.27 inches.

21. A method of making an endoluminal graft prosthesis for implantation into a patient, comprising

providing a graft comprising a graft fabric having a plurality of yarns, the yarns having a denier of from 5 to 50;

treating the graft fabric with a hydrophilic material;

attaching a stent to the graft fabric to form a stent graft; and

inserting the stent graft into an endovascular delivery system having a diameter of from about 0.06 inches to about 0.27 inches.