Microfluidic system with feedback control
First Claim
1. A microfluidic system for extracting a bodily fluid sample and monitoring an analyte in the bodily fluid sample, the microfluidic system comprising:
- an analysis module including;
at least one micro-channel for receiving and transporting a bodily fluid sample;
at least one analyte sensor for measuring an analyte in the bodily fluid sample, each of the at least one analyte sensors being in operative communication with a micro-channel; and
at least one position electrode, each of the at least one position electrodes in operative communication with at least one micro-channel;
a sampling module configured to extract the bodily fluid sample from a target site of a user'"'"'s body and transport the bodily fluid sample to the at least one micro-channel;
a meter configured for measuring an electrical characteristic of the at least one position electrode, the electrical characteristic being dependent on a position of the liquid sample in the micro-channel in operative communication with the at least one position electrode for which an electrical characteristic is measured; and
a feedback controller adapted to control the flow of bodily fluid sample through the microfluidic system based on the electrical characteristic measured by the meter.
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Accused Products
Abstract
A microfluidic system for extracting a bodily fluid sample (e.g., an interstitial fluid sample) and monitoring an analyte therein includes an analysis module, a sampling module, a meter and a feedback controller. The analysis module has a micro-channel(s) for receiving and transporting the bodily fluid sample, an analyte sensor(s) in operative communication with the micro-channel for measuring an analyte in the bodily fluid sample, and a position electrode in operative communication with the micro-channel. The sampling module is configured to extract the bodily fluid sample from a target site of a user'"'"'s body and transport the bodily fluid sample to the micro-channel. The sampling module includes a pressure ring(s) adapted to apply pressure to the user'"'"'s body in the vicinity of the target site. The meter is configured for measuring an electrical characteristic of the position electrode(s). Moreover, the electrical characteristic measured by the meter is dependent on a position of the liquid sample in the micro-channel and the feedback controller is adapted to control the flow of bodily fluid sample through the microfluidic system based on the measured electrical characteristic.
26 Citations
12 Claims
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1. A microfluidic system for extracting a bodily fluid sample and monitoring an analyte in the bodily fluid sample, the microfluidic system comprising:
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an analysis module including;
at least one micro-channel for receiving and transporting a bodily fluid sample;
at least one analyte sensor for measuring an analyte in the bodily fluid sample, each of the at least one analyte sensors being in operative communication with a micro-channel; and
at least one position electrode, each of the at least one position electrodes in operative communication with at least one micro-channel;
a sampling module configured to extract the bodily fluid sample from a target site of a user'"'"'s body and transport the bodily fluid sample to the at least one micro-channel;
a meter configured for measuring an electrical characteristic of the at least one position electrode, the electrical characteristic being dependent on a position of the liquid sample in the micro-channel in operative communication with the at least one position electrode for which an electrical characteristic is measured; and
a feedback controller adapted to control the flow of bodily fluid sample through the microfluidic system based on the electrical characteristic measured by the meter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification