Method of coating implantable medical devices

• US 20060019023A1
• Filed: 09/22/2005
• Published: 01/26/2006
• Est. Priority Date: 12/28/2001
• Status: Abandoned Application

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Hossainy, Syed F.A.
• Application Number:
  US11/233,991
• Publication Number:
  US 20060019023A1
• Time in Patent Office: Days
• US Class Current: 427/2.100
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: B05B 13/0228 the movement of the objects being rotative B05B13/0242 takes precedence
• CPC Class Codes: B05B 3/001 incorporating means for heating or cooling, e.g. the material to be sprayed
• CPC Class Codes: B05B 3/1014 with a spraying edge, e.g. like a cup or a bell
• CPC Class Codes: Y10S 118/16 Slinger type

Abstract

A method of coating a medical device, such as a stent is provided.

Claims

1. A method for coating an implantable medical device, comprising forming a polymer layer containing a drug on the device, applying a polymer melt free from any solvents to the polymer layer to form a topcoat layer, wherein the during the application of the polymer melt the migration of the drug from the polymer layer is prevented or significantly minimized.

2. The method of claim 1, wherein free from any solvents is defined as less than 20% by volume of solvent.

3. The method of claim 1, wherein free from any solvents is defined as less than 15% by volume of solvent.

4. The method of claim 1, wherein free from any solvents is defined as less than 10% by volume of solvent.

5. The method of claim 1, wherein free from any solvents is defined as less than 5% by volume of solvent.

6. The method of claim 1, wherein free from any solvents is defined as less than 1% by volume of solvent.

7. The method of claim 1, wherein free from any solvents is defined as 0% by volume of solvent.

8. The method of claim 1, wherein the applying a polymer melt comprises applying polymer to a disk member and spinning the disk member about an axis of the disk member such that the force that is applied to the polymer melt by the disk member discharges the polymer melt off of the disk member and onto the stent.

9. A method for coating an implantable medical device, comprising forming a polymer layer containing a drug on the device, applying a polymer in a liquid state and free from any solvents to the polymer layer to form a topcoat layer, wherein the during the application of the topcoat layer the migration of the drug from the polymer layer is prevented or significantly minimized.

10. The method of claim 9, wherein the temperature of the polymer in the liquid state is equal to or greater than the melting temperature of the polymer.