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METHOD AND APPARATUS FOR NUCLEIC ACID SEQUENCING AND IDENTIFICATION

  • US 20060019247A1
  • Filed: 05/20/2002
  • Published: 01/26/2006
  • Est. Priority Date: 05/20/2002
  • Status: Active Grant
First Claim
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1. A method comprising:

  • a) placing a template nucleic acid into four chambers, each chamber being associated with different nanopores and each chamber to comprising a different of labeled nucleotide;

    b) synthesizing a labeled nucleic acid from the template nucleic acid;

    c) contacting the labeled nucleic acid in each chamber with a its associated nanopore, wherein the labeled nucleic acid passes through the associated nanopore;

    d) detecting a labeled nucleotide;

    e) compiling a nucleotide distance map for each type of labeled nucleotide; and

    f) determining the sequence of the nucleic acid from the nucleotide distance maps.

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