Hybrid device for cell therapies
First Claim
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1. A device for receiving implanted biological material comprising:
- a porous outer wall defining an inner space and a fluid manifold assembly for selectively infusing at least one of immunosuppressive and/or growth factor media to said space and a pump or a reservoir for such media, operatively coupled to said manifold assembly.
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Abstract
A device for receiving implanted biological material includes a porous outer wall defining an inner space, a fluid manifold assembly for selectively infusing at least one of immunosuppressive and growth factor media to said space, and a pump structure operatively coupled to the manifold assembly. The device may comprise an additional plunger body for being disposed in said space and so as to define a peripheral gap between the plunger and the perforated wall of the device.
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Citations
21 Claims
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1. A device for receiving implanted biological material comprising:
- a porous outer wall defining an inner space and a fluid manifold assembly for selectively infusing at least one of immunosuppressive and/or growth factor media to said space and a pump or a reservoir for such media, operatively coupled to said manifold assembly.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for implanting biological material in a patient, comprising:
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providing a device for receiving biological material, said device including a porous outer wall defining an inner space and a fluid manifold assembly for selectively infusing at least one of immunosuppressive and/or growth factor media to said inner space and a pump or a reservoir for such media, operatively coupled to said manifold assembly;
implanting said device at a selected location within the patient;
allowing tissue ingrowth through said porous outer wall into said inner space;
disposing a biological material comprising a selected tissue/cell product within said inner space; and
selectively infusing at least one of immunosuppressive and/or growth factor media to said inner space. - View Dependent Claims (18, 19, 20, 21)
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Specification