Pharmaceutical compositions suitable for the treatment of ophthalmic diseases
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Abstract
Pharmaceutical compositions for the treatment of ophthalmic diseases, suitable for topical ocular administration and for systemic administration, comprising solid lipid nanoparticles (SLNs) with a mean diameter comprised between 50 and 400 nm wherein, within said nanoparticles, a pharmacologically active substance for the specific ophthalmic treatment is incorporated.
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Citations
21 Claims
- 1. (canceled)
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- 11. A therapeutic method for the treatment of ophthalmic diseases comprising the intravenous or topical ocular administration of a therapeutically effective amount of a pharmaceutical composition comprising solid lipidic nanoparticles containing a pharmacologically active substance suitable for the treatment of said ophthalmic diseases.
- 14. A pharmaceutical composition suitable for the treatment of ophthalmic diseases by intravenous or topical ocular administration, consisting essentially of an isotonic aqueous dispersion of solid lipid nanoparticles (SLNS) having a mean diameter comprised between 50 and 400 nm and polydispersion comprised between 50 and 400 nm and polydispersion comprised between 0.06 and 0.30, a pharmacologically active substance for the treatment of said diseases being incorporated within said SLNs.
Specification