Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
First Claim
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1. A method of determining a concentration of glucose in blood, the method comprising steps of:
- stimulating a region of skin other than the fingertips for at least 1 second;
after stimulating the region of skin, creating an opening in the region of skin to obtain a blood sample from the region;
coupling an electrochemical sensor strip to a meter;
contacting the sensor strip to the blood sample;
transporting no more than 1 microliter of blood sample to the sensor strip; and
determining the concentration of glucose in the blood sample using the electrochemical sensor strip and meter.
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Abstract
A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g., glucose) in the body fluid is then determined. It is found that the stimulation of the skin provides results that are generally closer to the results of measurements from the fingertips, the traditional site for obtaining body fluid for analyte testing.
350 Citations
18 Claims
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1. A method of determining a concentration of glucose in blood, the method comprising steps of:
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stimulating a region of skin other than the fingertips for at least 1 second;
after stimulating the region of skin, creating an opening in the region of skin to obtain a blood sample from the region;
coupling an electrochemical sensor strip to a meter;
contacting the sensor strip to the blood sample;
transporting no more than 1 microliter of blood sample to the sensor strip; and
determining the concentration of glucose in the blood sample using the electrochemical sensor strip and meter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification