Composition comprising an array which further comprises chimeric compositions
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Accused Products
Abstract
This invention provides novel compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such compositions and processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the compositions and processes of this invention.
43 Citations
861 Claims
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1. (canceled)
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2-838. -838. (canceled)
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839. A composition of matter that comprises
an array of solid surfaces comprising a plurality of discrete areas; wherein at least two of said discrete areas comprise;
a chimeric composition comprising;
a nucleic acid portion; and
a non-nucleic acid portion;
wherein said nucleic acid portion of a first discrete area has the same sequence as the nucleic acid portion of a second discrete area; and
wherein said non-nucleic acid portion has a binding affinity for analytes of interest.- View Dependent Claims (840, 841, 842, 843, 844, 845, 846, 847, 848)
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849. A composition of matter that comprises
an array of solid surfaces comprising a plurality of discrete areas; wherein at least two of said discrete areas comprise;
a chimeric composition hybridized to complementary sequences of nucleic acids fixed or immobilized to said discrete areas, wherein said chimeric composition comprises;
a nucleic acid portion; and
a non-nucleic acid portion;
said nucleic acid portion comprising at least one sequence, wherein said non-nucleic acid portion has a binding affinity for analytes of interest, and wherein when said non-nucleic acid portion is a peptide or protein, said nucleic acid portion does not comprises sequences which are either identical or complementary to sequences that code for said peptide or protein. - View Dependent Claims (850, 851, 852, 853, 854, 855, 856, 857, 858, 859, 860)
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861-952. -952. (canceled)
Specification