Method of storing substrate having active group or probe molecule immobilized thereon using UV film, method of producing microarray using the UV film, and substrate having the UV film attached thereto
First Claim
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1. A method of storing a substrate having an active group or a probe molecule immobilized thereon, comprising:
- attaching a UV film to a surface of the substrate having the active group or probe immobilized thereon; and
exposing the UV film to UV light, wherein the UV film comprises a UV-permeable base film and a pressure sensitive adhesive layer formed on a surface of the UV-permeable base film to immobilize the substrate, and when the pressure sensitive adhesive layer is exposed to the UV light, its adhesive force decreases.
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Abstract
Provided is a method of storing a substrate having an active group or a probe molecule immobilized thereon. The method includes attaching a UV film to a surface of the substrate having the active group or probe immobilized thereon; and exposing the UV film to UV light, wherein the UV film comprises a UV-permeable base film and a pressure sensitive adhesive layer formed on a surface of the UV-permeable base film to immobilize the substrate, and when the pressure sensitive adhesive layer is exposed to the UV light, its adhesive force decreases.
8 Citations
11 Claims
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1. A method of storing a substrate having an active group or a probe molecule immobilized thereon, comprising:
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attaching a UV film to a surface of the substrate having the active group or probe immobilized thereon; and
exposing the UV film to UV light, wherein the UV film comprises a UV-permeable base film and a pressure sensitive adhesive layer formed on a surface of the UV-permeable base film to immobilize the substrate, and when the pressure sensitive adhesive layer is exposed to the UV light, its adhesive force decreases. - View Dependent Claims (3, 4)
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2. The method of claim 2, wherein the pressure sensitive adhesive layer comprises
at least one elastomer selected from the group consisting of a polymer comprising acrylic acid ester copolymer, and a saturated copolyester comprising dibasic carboxylic acid and dihydroxy alcohol; -
15-200 parts by weight of UV-polymerizable acrylic acid ester having at least two acryloyl or methacryloyl groups and a molecular weight of 1000 or less, based on 100 parts by weight of the elastomer;
10-200 parts by weight of a tackifier based on 100 parts by weight of the elastomer;
1-100 parts by weight of anhydrous silica powders based on 100 parts by weight of the elastomer; and
a photopolymerization initiator in an amount sufficient to induce photopolymerization of the UV-polymerizable acrylic acid ester. - View Dependent Claims (10)
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5. A method of producing a microarray, comprising:
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attaching a UV film to a surface of a substrate having a probe molecule immobilized thereon in predetermined regions;
exposing the UV film to UV light; and
dicing the resultant product to obtain a unit microarry, wherein the UV film comprises a UV-permeable base film and a pressure sensitive adhesive layer formed on a surface of the UV-permeable base film to immobilize the substrate, and when the pressure sensitive adhesive layer is exposed to the UV light, its adhesive force decreases. - View Dependent Claims (6, 7, 8, 11)
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9. A substrate having a UV film attached thereto, the substrate produced using a method comprising:
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attaching the UV film to a surface of a substrate having an active group or a probe molecule immobilized thereon; and
exposing the UV film to UV light, wherein the UV film comprises a UV-permeable base film and a pressure sensitive adhesive layer formed on a surface of the UV-permeable base film to immobilize the substrate, and when the pressure sensitive adhesive layer is exposed to the UV light, its adhesive force decreases.
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Specification