DYNAMICALLY CONTROLLABLE BIOLOGICAL/CHEMICAL DETECTORS HAVING NANOSTRUCTURED SURFACES
First Claim
1. A detector comprising:
- a surface having a plurality of nanostructured projections disposed thereon, the projections having tips;
a reagent pixel on the surface, between a plurality of the projections;
means for moving a liquid across tips of the nanostructured projections without contacting the reagent pixel; and
means for moving the liquid toward said surface in a way such that the liquid contacts said reagent pixel.
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Accused Products
Abstract
A biological/chemical detector is disclosed that is capable of manipulating liquids, such as reagent droplets, without relying on microchannels. In a first embodiment, fluid flow is passed through the detector, thus causing particles wholly or partially containing an illustrative chemical compound or biological species to be collected on the tips of nanostructures in the detector. A droplet of liquid is moved across the tips of the nanostructures, thus absorbing the particles into the liquid. The droplet is caused to penetrate the nanostructures in a desired location, thus causing the chemical compound or biological species in said liquid droplet to come into contact with, for example, a reagent. In another embodiment, a fluid flow is passed through the nanostructured surfaces of the detector such that the chemical compound and/or biological species are deposited between the nanoposts of a desired pixel. A droplet of liquid is moved across the surface to that desired pixel and is caused to penetrate the nanostructures of the pixel, thus contacting a reagent.
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Citations
31 Claims
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1. A detector comprising:
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a surface having a plurality of nanostructured projections disposed thereon, the projections having tips;
a reagent pixel on the surface, between a plurality of the projections;
means for moving a liquid across tips of the nanostructured projections without contacting the reagent pixel; and
means for moving the liquid toward said surface in a way such that the liquid contacts said reagent pixel. - View Dependent Claims (2, 3, 4, 5, 6, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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7-17. -17. (canceled)
Specification