Vessel isolation device

• US 20060041269A1
• Filed: 08/18/2004
• Published: 02/23/2006
• Est. Priority Date: 08/18/2004
• Status: Active Grant

• Current Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Original Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Inventors: Horrigan, John B.
• Granted Patent: US 7,819,841 B2
• Time in Patent Office: Days
• US Class Current: 606/198
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/12127 Double occlusion, e.g. for creating blood-free anastomosis site

Abstract

The device utilizes a reversible body partially covered by a blood impermeable sleeve. The device has a low profile collapsed state for delivery and a expanded state for deployment. The impermeable sleeve extends from a proximal portion to a distal portion of the expandable body and generally follows the contour of the expandable body. When deployed, the device is configured in the expanded state and has a generally hourglass, or dumbbell shape. In the expanded state, portions of the sleeve adjacent to the proximal and distal portions are placed in apposition to a vessel wall and blood is free to flow through the expandable body via inlets and outlets provided in the proximal and distal portions. As a result, an isolated treatment space is created that surrounds the device between the vessel wall and the blood impermeable sleeve adjacent to the neck portion of the expandable body.

Claims

1. A vessel isolation device, comprising:

a noninflatable expandable body, reversibly expandable from a low profile collapsed state to a generally hourglass-shaped expanded state, including

a proximal portion having at least one inlet formed therein,

a distal portion having at least one outlet formed therein, the outlet being in fluid communication with the inlet, and

a neck portion disposed between the proximal and distal portions; and

a blood impermeable sleeve disposed about the neck portion of the expandable body and at least a portion of the proximal and distal portions of the expandable body, the sleeve being reversibly expandable with the expandable body from the collapsed state to the expanded state,

wherein the sleeve is placed in apposition to a vessel wall adjacent to the proximal portion and the distal portion when the expandable body is in the expanded state, creating an isolated treatment space.

2. The vessel isolation device of claim 1, wherein the neck portion is expandable.

3. The vessel isolation device of claim 1, wherein the expandable body is formed of a braided structure.

4. The vessel isolation device of claim 1, wherein the expandable body is self-expanding.

5. The vessel isolation device of claim 4, wherein the expandable body is constructed of nitinol.

6. The vessel isolation device of claim 1, wherein the expandable body is constructed from a plurality of braided structures.

7. The vessel isolation device of claim 6, wherein the plurality of braided structures are interconnected by at least one neck element.

8. The vessel isolation device of claim 1, wherein the sleeve is an inelastic material.

9. The vessel isolation device of claim 8, wherein the material of the sleeve is selected from the group consisting of polyester and polytetrafluoroethylene.

10. The vessel isolation device of claim 1, wherein the sleeve is an elastic material.

11. The vessel isolation device of claim 10, wherein the sleeve is selected from the group consisting of natural rubber, silicone rubber, latex rubber, thermoplastic elastomer, and polyurethane elastomer.

12. The vessel isolation device of claim 1, further comprising:

a first radiopaque marker disposed on the distal portion; and

a second radiopaque marker disposed on the proximal portion.

13. The vessel isolation device of claim 1, further comprising:

at least one radiopaque marker located on the neck portion.

14. The vessel isolation device of claim 1, further comprising:

a first radiopaque marker disposed on a distal end of the distal portion;

a second radiopaque marker disposed on a distal end of the neck portion;

a third radiopaque marker disposed on a proximal end of the neck portion; and

a fourth radiopaque marker disposed on a proximal end of the proximal portion.

15. The vessel isolation device of claim 1, further comprising:

at least one catheter tube defining an access lumen, wherein the catheter tube is coupled to the blood impermeable sleeve such that the access lumen is placed in fluid communication with the isolated treatment space at an access port.

16. A vessel isolation system, comprising

a noninflatable expandable body, reversibly expandable from a low profile collapsed state to a generally hourglass-shaped expanded state, including

a proximal portion having at least one inlet formed therein,

a distal portion having at least one outlet formed therein, the outlet being in fluid communication with the inlet, and

a neck portion disposed between the proximal and distal portions;

a blood impermeable sleeve disposed about the neck portion of the expandable body and at least a portion of the proximal and distal portions of the expandable body, the sleeve being reversibly expandable with the expandable body from the collapsed state to the expanded state,

wherein the sleeve is placed in apposition to a vessel wall adjacent to the proximal portion and the distal portion when the expandable body is in the expanded state, creating an isolated treatment space; and

means for deploying the expandable body from the collapsed state to the expanded state.

17. The vessel isolation system of claim 16, further comprising:

a guidewire coupled to the expandable body.

18. The vessel isolation system of claim 17, wherein the guidewire is slidably coupled to the expandable body at a proximal end of the proximal portion and rotatably coupled to the expandable body at a distal end of the distal portion.

19. The vessel isolation system of claim 17, wherein the guidewire is slidably coupled to the expandable body at a distal end of the distal portion and rotatably coupled to the expandable body at a proximal end of the proximal portion.

20. The vessel isolation system of claim 16, wherein the deploying means is a mechanical linkage that allows the user to mechanically deploy the expandable body.

21. The vessel isolation system of claim 16, wherein the deploying means is a sheath retractable from a position surrounding the expandable body such that when the sheath is retracted, the expandable body is able to expand.

22. The vessel isolation system of claim 16, wherein the expandable body is self-expanding.

23. A method of treating a vessel comprising:

providing a noninflatable, expanding vessel isolation device;

locating the vessel isolation device at a treatment site in a collapsed state such that a proximal portion of the vessel isolation device is proximal of the treatment site and a distal portion of the vessel isolation device is distal of the treatment site;

expanding the vessel isolation device from a collapsed state to an expanded state;

applying a treatment to the vessel;

collapsing the vessel isolation device from the expanded state to the collapsed state; and

removing the vessel isolation device from the vessel.