Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer

• US 20060046257A1
• Filed: 01/27/2005
• Published: 03/02/2006
• Est. Priority Date: 01/27/2004
• Status: Active Grant

• Current Assignee: Compugen Ltd
• Original Assignee: Compugen Ltd
• Inventors: Novik, Amit, Walach, Shira, Toporik, Amir, Sameah-Greenwald, Shirley, Levine, Zurit, Pollock, Sarah, Akiva, Pinchas, Ayalon-Soffer, Michal, Sella-Tavor, Osnat, Dahary, Dvir, Diber, Alexander, Shemesh, Ronen, Sorek, Rotem, Keren, Naomi, Cojocaru, Gad S.
• Granted Patent: US 7,569,662 B2
• Time in Patent Office: Days
• US Class Current: 435/6
• CPC Class Codes: C12Q 1/6886 for cancer immunoassay for cancer G01N33/574
• CPC Class Codes: C12Q 2600/112 Disease subtyping, staging or classification
• CPC Class Codes: G01N 33/57423 of lung

Abstract

Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.

Claims