Drug delivery apparatus and method for automatically reducing drug dosage
First Claim
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1. A fluid drug delivery device comprising:
- a reservoir for storing a fluid;
a catheter for transferring fluid from said reservoir to a selected body site, said catheter having a proximal end for receiving fluid from said reservoir and a distal end for delivering fluid to said body site;
a controllable fluid transfer device coupling said reservoir to said catheter proximal end;
a controller storing data defining a delivery rate specifying a quantity of fluid to be delivered to said catheter within a specified period;
a source of modification data;
said controller being responsive to said modification data for iteratively modifying said stored delivery rate; and
wherein said fluid transfer device is responsive to said modified delivery rate for delivering a specified quantity of fluid to said catheter proximal end.
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Abstract
A drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump mechanism or valve, and a drug delivery control means. The drug delivery control means comprises a controller, e.g., a microprocessor or microcontroller which is operable to automatically reduce the rate of drug delivery over a certain reduction interval (e.g., multiple days) from an initial dosage value to a final dosage value.
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Citations
16 Claims
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1. A fluid drug delivery device comprising:
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a reservoir for storing a fluid;
a catheter for transferring fluid from said reservoir to a selected body site, said catheter having a proximal end for receiving fluid from said reservoir and a distal end for delivering fluid to said body site;
a controllable fluid transfer device coupling said reservoir to said catheter proximal end;
a controller storing data defining a delivery rate specifying a quantity of fluid to be delivered to said catheter within a specified period;
a source of modification data;
said controller being responsive to said modification data for iteratively modifying said stored delivery rate; and
whereinsaid fluid transfer device is responsive to said modified delivery rate for delivering a specified quantity of fluid to said catheter proximal end. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method of operating an implantable drug delivery device for transferring a drug from a reservoir to a catheter for delivery to a body site, said method including:
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providing said reservoir with a first drug;
storing a current dosage value;
generating dosage modification data;
periodically modifying said stored dosage value in accordance with said dosage modification data; and
controllably transferring said first drug from said reservoir to said catheter in accordance with the currently stored dosage value. - View Dependent Claims (9, 10)
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11. A fluid drug delivery system comprising:
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an implantable drug delivery pump including a controller for transferring a fluid drug from said pump at delivery rates defined by a stored drug delivery profile;
an external programmer for generating drug delivery modification data;
and wherein said controller includes means responsive to said drug modification data for iteratively modifying said defined delivery rates as a function of said modification data. - View Dependent Claims (12, 13, 14, 15, 16)
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Specification