Contrast agent imaging-driven health care system and method

• US 20060052690A1
• Filed: 09/08/2004
• Published: 03/09/2006
• Est. Priority Date: 09/08/2004
• Status: Abandoned Application

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Mack, David Charles, Sirohey, Saad Ahmed, Avinash, Gopal B., Fox, Stanley Haim
• Application Number:
  US10/935,893
• Publication Number:
  US 20060052690A1
• Time in Patent Office: Days
• US Class Current: 600/420
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039

Abstract

Procedures for providing health care to a range of anatomies that require contrast agents for adequate imaging. Image data is acquired in accordance with a range of modalities, and at different times and on different patients, depending upon the particular implementation. The image data is processed in accordance with one of a range of manners and algorithms for a particular purpose and a specific tissue or organ. The resulting workflow paths provide novel combinations for rendering health care to specific tissues and organs by the use of contrast agent-based imaging.

Claims

1. A method for evaluating health of liver tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent for tissue of the liver during at least two phases of progression of the contrast agent; and

processing the image data to analyze features of interest in the tissue.

2. The method of claim 1, wherein the image data is acquired during at least two of an arterial phase, a delayed arterial phase and a portal venous phase of contrast agent progression.

3. The method of claim 1 wherein the image data is processed to identify hepatocellular cancers or metastatic tumors in the tissue.

4. The method of claim 1, wherein the accessed image data is produced via a high speed computed tomography scanning sequence.

5. The method of claim 1, wherein at least one diagnostic image is generated based upon the accessed image data.

6. The method of claim 5, wherein the at least one diagnostic image includes features discernable during each of the at least two phases of contrast agent progression.

7. A method for evaluating health of liver tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent for tissue of the liver during an arterial or delayed arterial phase of progression of the contrast agent; and

processing the image data to analyze features of interest in the tissue.

8. The method of claim 7, comprising accessing image data for the tissue of the liver during at least one additional phase of progression of contrast agent and processing the image data to analyze additional features of interest in the tissue.

9. The method of claim 7, wherein the feature of interest includes hepatocellular carcinomas.

10. The method of claim 7, wherein the accessed image data is produced via a high speed computed tomography scanning sequence.

11. The method of claim 7, wherein at least one diagnostic image is generated based upon the accessed image data.

12. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, fat tissue, vascular tissue, tumor tissue, stones, kidney tissue or pancreas tissue, the data including multi-phase scan data, temporal data, multi-modal data or multi-patient data; and

analyzing the data via a segmentation algorithm adapted for detection of the tissue, diagnosis of disease of the tissue, establishment of a care plan for medical treatment of the tissue, medical treatment of the tissue, transplantation of replacement tissue, follow-up on treatment of the tissue, analysis of health of the tissue or image guided surgery on the tissue.

13. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, fat tissue, vascular tissue, tumor tissue, stones, kidney tissue or pancreas tissue, the data including multi-phase scan data, temporal data, multi-modal data or multi-patient data; and

analyzing the data via a sizing algorithm, the algorithm being adapted for detection of health of the tissue, diagnosis of disease of the tissue, establishment of a care plan for medical treatment of the tissue, medical treatment of the tissue;

transplantation of replacement tissue, follow-up on treatment of the tissue, or analysis of health of the tissue.

14. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, fat tissue, vascular tissue, tumor tissue, stones, kidney tissue or pancreas tissue, the data including multi-phase scan data, temporal data, multi-modal data or multi-patient data; and

analyzing the data via a visualization algorithm, the algorithm being adapted for detection of health of the tissue, establishment of a care plan for medical treatment of the tissue, transplantation of replacement tissue, follow-up on treatment of the tissue, analysis of health of the tissue or image guided surgery on the tissue.

15. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, fat tissue, vascular tissue, tumor tissue, stones, kidney tissue or pancreas tissue, the data including multi-phase scan data, temporal data, perfusion data, or multi-modal data; and

analyzing the data via a registration algorithm, the algorithm being adapted for detection of health of the tissue, diagnosis of disease of the tissue, establishment of a care plan for medical treatment of the tissue, medical treatment of the tissue, transplantation of replacement tissue, follow-up on treatment of the tissue or performing image guided surgery on the tissue.

16. Method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of vascular tissue, tumor tissue, stones, the data including single-phase scan data, multi-phase scan data, or multi-modal data; and

analyzing the data via a shape-based analysis algorithm, the algorithm being adapted for detection of the tissue, establishment of a care plan for medical treatment of the tissue or performing minimally invasive surgery on the tissue.

17. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, vascular tissue, tumor tissue, kidney tissue or pancreas tissue, the data including multi-phase scan data, perfusion data, multi-modal data or multi-patient data; and

analyzing the data via a delineation algorithm, the algorithm being adapted for diagnosis of disease of the tissue, establishment of a care plan for medical treatment of the tissue, medical treatment of the tissue, transplantation of replacement tissue, analysis of health of the tissue or performing image guided surgery on the tissue.

18. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, tumor tissue, stones, kidney tissue or pancreas tissue, the data including multi-phase scan data, temporal data, multi-modal data or multi-patient data; and

analyzing the data via a volumetric analysis algorithm, the algorithm being adapted for establishment of a care plan for medical treatment of the tissue, transplantation of replacement tissue, follow-up on treatment of the tissue, or analysis of health of the tissue.

19. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, tumor tissue, stones, kidney tissue or pancreas tissue, the data including single-phase scan data, multi-phase scan data, temporal data, multi-modal data or multi-patient data; and

analyzing the data via a modeling algorithm, the algorithm being adapted for establishment of a care plan for medical treatment of the tissue, medical treatment of the tissue;

transplantation of replacement tissue, analysis of health of the tissue or performing image guided surgery on the tissue.

20. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver tissue, vascular tissue, tumor tissue, kidney tissue or pancreas tissue, the data including single-phase scan data, multi-phase scan data, multi-modal data; and

analyzing the data via a surgical navigation algorithm, the algorithm being adapted for treatment of the tissue or performing image guided surgery on the tissue.

21. A method for evaluating health of tissue comprising:

accessing image data encoding contrast produced as a result of administration of a contrast agent to at least one subject to produce data for an image of liver, the data including single-phase scan data, multi-phase scan data, or multi-modal data; and

analyzing the data via a texture-based analysis algorithm, the algorithm being adapted for detection of the tissue, establishment of a care plan for medical treatment of the tissue or performing minimally invasive surgery on the tissue.

22. A method for evaluating health of tissue comprising:

accessing image data for an image of liver tissue, the data including single modality scan data, or multi-modal data; and

analyzing the data via a texture-based analysis algorithm, the algorithm being adapted for detection of the tissue, establishment of a care plan for medical treatment of the tissue or performing minimally invasive surgery on the tissue.

23. A method for evaluating health of tissue comprising:

accessing image data acquired following administration of a contrast agent to at least one subject to produce data for an image of sascular tissue, tumor tissue, or stones, the data including single-phase scan data, multi-phase scan data, or multi-modal data; and

analyzing the data via a shape-based or texture-based analysis algorithm, the algorithm being adapted for detection of the tissue, establishment of a care plan for medical treatment of the tissue or performing minimally invasive surgery on the tissue.

24. A method for evaluating drug treatment for cancer, the method comprising:

accessing image data acquired following administration of a contrast agent to at least one subject;

delineating tissue suspect of disease;

registering tissue across multiple phases of contrast agent progression in the tissue; and

analyzing contract agent progression through the tissue to characterize drug treatment response.