Interstitial fluid analyzer
First Claim
1. An apparatus for measuring an analyte in interstitial fluid of an animal, comprising:
- an array chamber comprising an array of one or more microprojections;
a detection compartment comprising a sensor in selective fluid communication with the array chamber;
two extraction electrodes for inducing electrotransport of the interstitial fluid from the animal to the array chamber; and
an electronic control module.
3 Assignments
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Accused Products
Abstract
A device useful for measuring an analyte in the interstitial fluid of an animal comprising an array chamber having an array of one or more microprojections and a detection compartment comprising a sensor in selective fluid communication with the array chamber. Also included are two extraction electrodes for inducing electrotransport of the interstitial fluid from the animal into the array chamber. A method includes the steps of forming a plurality of microchannels through a stratum corneum layer of an epidermis of the animal, inducing electrotransport of interstitial fluid containing the analyte through the microchannels and mixing one or more materials with the interstitial fluid to form a mixture, contacting the mixture with detection electrodes and analyzing the mixture with the detection electrodes.
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Citations
57 Claims
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1. An apparatus for measuring an analyte in interstitial fluid of an animal, comprising:
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an array chamber comprising an array of one or more microprojections;
a detection compartment comprising a sensor in selective fluid communication with the array chamber;
two extraction electrodes for inducing electrotransport of the interstitial fluid from the animal to the array chamber; and
an electronic control module. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
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40. A method for measuring an analyte in interstitial fluid of an animal, comprising forming a plurality of microchannels through a stratum corneum layer of an epidermis of the animal;
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inducing electrotransport of interstitial fluid containing the analyte through the microchannels;
mixing one or more materials with the interstitial fluid to form a mixture;
contacting the mixture with detection electrodes; and
conducting amperometric analysis on the mixture with the detection electrodes. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57)
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Specification