Optical examination of biological tissue using non-contact irradiation and detection
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Abstract
An optical system for examination of biological tissue includes a light source, a light detector, optics and electronics. The light source generates a light beam, transmitted to the biological tissue, spaced apart from the source. The light detector is located away (i.e., in a non-contact position) from the examined biological tissue and is constructed to detect light that has migrated in the examined tissue. The electronics controls the light source and the light detector, and a system separates the reflected photons (e.g., directly reflected or scattered from the surface or superficial photons) from the photons that have migrated in the examined tissue. The system prevents detection of the “noise” photons by the light detector or, after detection, eliminates the “noise” photons in the detected optical data used for tissue examination.
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Citations
39 Claims
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1-13. -13. (canceled)
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14. An optical system for examination of biological tissue, comprising:
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a light source for generating a light beam to be transmitted to the biological tissue spaced apart from said source;
a light detector located away from the examined biological tissue and constructed to detect light that has migrated in the examined biological tissue;
a module constructed and arraged to deliver a chemical or pharmacological agent into the examined tissue; and
electronics for controlling said light source and said light detector and a system for separating reflected photons from photons that have migrated in the examined biological tissue to prevent detection of the reflected photons by the light detector. - View Dependent Claims (15, 16, 17, 18)
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19. An optical method for examination of biological tissue, comprising:
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generating a light beam from a light source and transmitting said light beam to the biological tissue spaced apart from said source;
detecting by a light detector, located away from the examined biological tissue, light that has migrated in the examined biological tissue;
controlling operation of said light source and said light detector; and
separating reflected photons from photons that have migrated in the examined biological tissue to prevent detection of the reflected photons by the light detector or eliminating after detection the reflected photons in the detected optical data used for tissue examination. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
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Specification