Prosthetic valve with pores

• US 20060058889A1
• Filed: 08/31/2005
• Published: 03/16/2006
• Est. Priority Date: 09/10/2004
• Status: Active Grant

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: Case, Brian C., Osborne, Thomas A., Kirts, Beth Ann
• Granted Patent: US 7,361,189 B2
• Time in Patent Office: Days
• US Class Current: 623/23.680
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2230/0026 trapezoidal
• CPC Class Codes: A61F 2230/0095 Saddle-shaped

Abstract

Prosthetic valves for regulating fluid flow are provided. The valves have at least one leaflet that includes a plurality of pores that allow a quantity of retrograde flow to pass through the leaflet when the valve is in a closed configuration.

Claims

1. A valve for regulating fluid flow through a body vessel, the valve comprising:

a leaflet having a valve portion moveable between a first position that permits said fluid flow in a first direction and a second position that substantially prevents said fluid flow in a second, opposite direction, the leaflet defining a plurality of pores; and

means for maintaining an axial position of the leaflet in said body vessel.

2. A valve for regulating fluid flow through a body vessel according to claim 1, wherein at least one pore of the plurality of pores has a diameter between about 0.1 μ

m and about 10 mm.

3. A valve for regulating fluid flow through a body vessel according to claim 1, wherein at least one pore of the plurality of pores has a diameter between about 0.1 μ

m and about 1 mm.

4. A valve for regulating fluid flow through a body vessel according to claim 1, wherein at least one pore of the plurality of pores has a diameter between about 0.1 μ

m and about 0.1 mm.

5. A valve for regulating fluid flow through a body vessel according to claim 1, wherein at least one pore of the plurality of pores has a diameter between about 0.1 μ

m and about 1 μ

m.

6. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the plurality of pores has a mean diameter of between about 0.1 μ

m and about 10 mm.

7. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the plurality of pores has a mean diameter of between about 0.1 μ

m and about 1 mm.

8. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the plurality of pores has a mean diameter of between about 0.1 μ

m and about 0.1 mm.

9. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the plurality of pores has a mean diameter of between about 0.1 μ

m and about 1 μ

m.

10. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the leaflet has a second portion, a first pore of the plurality of pores is disposed on the valve portion, and a second pore of the plurality of pores is disposed on the second portion.

11. A valve for regulating fluid flow through a body vessel according to claim 10, wherein the first pore has a first diameter and the second pore has a second, different diameter.

12. A valve for regulating fluid flow through a body vessel according to claim 11, wherein the second diameter is larger than the first diameter.

13. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the leaflet is formed of a bioremodellable material.

14. A valve for regulating fluid flow through a body vessel according to claim 13, wherein the bioremodellable material comprises an extracellular matrix material.

15. A valve for regulating fluid flow through a body vessel according to claim 13, wherein the bioremodellable material comprises small intestine submucosa.

16. A valve for regulating fluid flow through a body vessel according to claim 1, wherein the leaflet comprises a mesh.

17. A valve for regulating fluid flow through a body vessel, the valve comprising:

a support frame having radially compressed and radially expanded configurations; and

at least one leaflet attached to the support frame and defining a plurality of pores, at least a portion of the leaflet being movable between a first position that permits fluid flow through said body vessel and a second position that substantially prevents fluid flow through said body vessel.

18. A valve for regulating fluid flow through a body vessel according to claim 17, wherein the plurality of pores comprises first and second sets of pores, the first set of pores having a first mean diameter and the second set of pores having a second mean diameter that is different than the first mean diameter.

19. A valve for regulating fluid flow through a body vessel according to claim 18, wherein the leaflet comprises first and second regions and the first set of pores is disposed on the first region and the second set of pores is disposed on the second region.

20. A valve for regulating fluid flow through a body vessel, the valve comprising a moveable leaflet defining a plurality of pores sized to permit a controlled amount of said fluid flow through the pores in a retrograde direction.