C-aryl glucoside SGLT2 inhibitors and method
2 Assignments
0 Petitions
Accused Products
Abstract
A compound of the formula I
168 Citations
16 Claims
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1. A compound of formula I
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2. A pharmaceutical composition comprising a compound of formula I and a pharmaceutically acceptable carrier therefore.
- 3. A pharmaceutical combination comprising a compound of formula I and at least one therapeutic agent selected from the group consisting of an antidiabetic agent, an anti-obesity agent, a anti-hypertensive agent, an anti-atherosclerotic agent and a lipid-lowering agent.
- 13. A method for treating or delaying the progression or onset of diabetes, diabetic retinopathy, diabetic neuropathy, diabetic nephropathy, delayed wound healing, insulin resistance, hyperglycemia, hyperinsulinemia, elevated blood levels of fatty acids or glycerol, hyperlipidemia, obesity, hypertriglyceridemia, Syndrome X, diabetic complications, atherosclerosis or hypertension, or for increasing high density lipoprotein levels, comprising administering a therapeutically effective amount of a compound of formula I.
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15. A method for treating type II diabetes comprising administering a therapeutically effective amount of a compound of formula I, alone or in combination with at least one other therapeutic agent selected from the group consisting of antidiabetic agent, an agent for treating the complications of diabetes, an anti-obesity agent, an antihypertensive agent, an antiplatelet agent, an anti-atherosclerotic agent and a hypolipidemic agent.
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16. A compound having the structure
Specification