Radiotherapy treatment monitoring using ultrasound
First Claim
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1. A method of assessing cell condition in response to treatment, the method comprising the steps of:
- a. obtaining a baseline ultrasound scan of a treatment area of a patient;
b. obtaining, subsequent to the baseline scan, one or more temporally distinct treatment ultrasound scans of the treatment area at various times during a course of treatment sessions;
c. comparing at least one of the one or more treatment ultrasound scans to the baseline ultrasound scan; and
d. based on the comparison, constructing a damage map representing cell damage within the treatment area.
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Abstract
Methods and systems for assessing the effects of therapy on a patient include obtaining baseline and treatment ultrasound scans of a treatment area of a patient where the treatment ultrasound scans are taken subsequent to the baseline scan and at various times during a course of radiotherapy treatment sessions. The baseline and treatment ultrasounds are compared, and as a result a damage map representing cell death within the treatment area can be constructed.
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Citations
32 Claims
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1. A method of assessing cell condition in response to treatment, the method comprising the steps of:
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a. obtaining a baseline ultrasound scan of a treatment area of a patient;
b. obtaining, subsequent to the baseline scan, one or more temporally distinct treatment ultrasound scans of the treatment area at various times during a course of treatment sessions;
c. comparing at least one of the one or more treatment ultrasound scans to the baseline ultrasound scan; and
d. based on the comparison, constructing a damage map representing cell damage within the treatment area. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A system for determining cell condition in response to treatment, the system comprising:
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a storage unit for receiving ultrasound scans of a treatment area, the ultrasound scans comprising;
a baseline ultrasound scan; and
one or more temporally distinct treatment ultrasound scans of the treatment area taken subsequent to the baseline scan and at various times during a course of treatment sessions; and
a comparator module for comparing the baseline ultrasound scan and at least one of the one or more treatment ultrasound scans and, based on the comparison, constructing a damage map representing cell condition within the treatment area. - View Dependent Claims (23, 24, 25, 26)
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27. An article of manufacture having computer-readable program portions embodied thereon for determining cell condition in response to treatment, the article comprising computer-readable instructions for:
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a. obtaining a plurality of temporally distinct ultrasound scans of a treatment area at various times during a course of treatment sessions;
c. comparing the plurality of ultrasound scans; and
d. constructing a damage map representing cell condition within the treatment area based on the comparison. - View Dependent Claims (28, 29, 30, 31, 32)
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Specification