Implantable medical device with his-purkinje activity detection

• US 20060064027A1
• Filed: 09/21/2004
• Published: 03/23/2006
• Est. Priority Date: 09/21/2004
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Combs, William J., Borowitz, Lynn A.
• Granted Patent: US 7,792,580 B2
• Time in Patent Office: Days
• US Class Current: 600/509
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3682 with a variable atrioventricular delay
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371

Abstract

Implantable medical devices having two or more leads can utilize digital signal processing to sample and filter the acquired data. The processed data is utilized to identify electrical activity in cardiac tissue remote from the lead location. An atrial lead and a ventricular lead are used to acquire data and the data is processed to indicated electrical timing with the HIS bundle.

Claims

1. An implantable medical device (IMD) comprising:

means for acquiring analog signals from cardiac activity;

means for converting the analog signals to digital signal;

means for processing the digital signals to identify HIS bundle electrical timing.

2. The IMD of claim 1, wherein the means for acquiring include an atrial lead and a ventricular lead.

3. The IMD of claim 2, wherein the means for processing include means for subtracting a ventricular signal from an atrial signal to produce a HIS signal.

4. The IMD of claim 3, further comprising means for filtering the HIS signal.

5. The IMD of claim 4, wherein the means for filtering include a bandpass filter.

6. The IMD of claim 5, wherein the bandpass filter is a 30 Hz bandpass filter.

7. The IMD if claim 3, further comprising means for averaging multiple HIS signals.

8. The IMD of claim 1, where the means for converting include a 12 bit A/D converter sampling at a rate of 1 kHz or greater.

9. An implantable medical device (IMD) comprising:

a processor;

an atrial lead electrically coupled with the processor and providing analog atrial data to the processor;

a ventricular lead electrically coupled with the processor and providing analog ventricular data to the processor;

an A/D converter in electrical communication with the processor for converting the analog atrial data and analog ventricular data to digital atrial data and digital ventricular data; and

a digital signal processing module in communication with the processor and including an algorithm to subtract the ventricular signal defined by the digital ventricular data from an atrial signal defined by the digital atrial data to produce a HIS signal.

10. A method of determining timing within a HIS bundle from an atrial and a ventricular lead, the method comprising:

sensing electrical activity within a ventricle via the ventricular lead;

sensing electrical activity with an atrium via the atrial lead;

sampling the sensed electrical activity from the atrium and from the ventricle to produce an atrial signal and a ventricular signal;

subtracting the ventricular signal from the atrial signal to produce a HIS signal; and

identifying the timing of HIS electrical activity from the HIS signal.

11. The method of claim 10, further comprising averaging a plurality of HIS signals prior to identifying the timing.

12. The method of claim 10, further comprising filtering the HIS signal prior to identifying the timing.

13. The method of claim 10, further comprising:

generating a baseline complex;

comparing the HIS signal to the baseline; and

discarding the HIS signal unless the HIS signal is temporally correlated to the baseline.