Heating/cooling system for indwelling heat exchange catheter

• US 20060064146A1
• Filed: 09/17/2004
• Published: 03/23/2006
• Est. Priority Date: 09/17/2004
• Status: Abandoned Application

• Current Assignee: Alsius Corporation
• Original Assignee: Alsius Corporation
• Inventors: Collins, Kenneth A.
• Application Number:
  US10/944,544
• Publication Number:
  US 20060064146A1
• Time in Patent Office: Days
• US Class Current: 607/105
• CPC Class Codes: A61F 2007/0054 with a closed fluid circuit, e.g. hot water
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities

Abstract

A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. A pump circulates the patient coolant to and from the catheter. The bath is kept at a minimum temperature and the pump stopped, with the pump being started immediately upon receiving a signal indicating that the patient'"'"'s temperature is rising above a desired setpoint.

Claims

1. A heat exchange system for cooling a patient coolant circulating through a closed loop intravenous catheter, comprising:

a cooling receptacle engageable with a portion of a path of the patient coolant outside the catheter;

a working fluid in thermal contact with the cooling receptacle at least to cool the patient coolant flowing through the path when the patient coolant is warmer than the working fluid;

a pump circulating patient coolant between the catheter and the path in the cooling receptacle;

a heat sink in thermal contact with the working fluid; and

a controller receiving a patient temperature signal and controlling the heat sink and pump such that the working fluid is maintained at a low temperature at least ten degrees Celsius below normal body temperature and the pump is deenergized when a patient in whom the catheter is intubated is at a target temperature, the controller energizing the pump when the patient'"'"'s temperature rises above the target temperature such that the patient is immediately cooled.

2. The system of claim 1, wherein the low temperature is at least twenty degrees Celsius below normal body temperature.

3. The system of claim 2, wherein the low temperature is no more than zero degrees Celsius.

4. The system of claim 1, wherein the patient coolant is saline and the path is defined at least in part by a tubing set that is disposable in the cooling receptacle.

5. The system of claim 1, wherein the target temperature is in the normothermia range and the pump is energized substantially as soon as the signal indicates that a patient is spiking a fever.

6. The system of claim 1, wherein the target temperature is in the mild or moderate hypothermia range and the pump is energized substantially as soon as the patient temperature drifts up from target temperature.

7. A patient temperature control system, comprising:

an intravascular closed loop catheter through which patient coolant circulates under the influence of a pump;

a cooling member holding working fluid in thermal contact with the patient coolant; and

a processor receiving a patient temperature signal and when the signal indicates that the patient is at or below a target temperature maintaining the working fluid substantially at zero degrees Celsius and the pump deenergized, the processor causing the pump to be energized when the patient temperature signal indicates that the patient'"'"'s temperature is rising above target temperature.

8. The system of claim 7, wherein the cooling member includes:

a cooling receptacle engageable with a portion of a path of the patient coolant outside the catheter, the working fluid being in thermal contact with the cooling receptacle at least to cool the patient coolant flowing through the path when the patient coolant is warmer than the working fluid; and

a heat sink in thermal contact with the working fluid, the processor controlling the heat sink and pump.

9. The system of claim 8, wherein the patient coolant is saline and the path is defined at least in part by a tubing set that is disposable in the cooling receptacle.

10. The system of claim 7, wherein the target temperature is in the normothermia range and the pump is energized substantially as soon as the signal indicates that a patient is spiking a fever.

11. The system of claim 7, wherein the target temperature is in the mild or moderate hypothermia range and the pump is energized substantially as soon as the patient temperature drifts up from target temperature.

12. A method for treating a patient, comprising:

advancing a closed loop heat exchange catheter into the vasculature of the patient;

circulating patient coolant through the catheter and past a working fluid using a pump to lower the temperature of the patient to a target temperature;

deenergizing the pump while maintaining the working fluid at a temperature of no more than ten degrees Celsius; and

upon indication of the patient'"'"'s temperature rising above target temperature, starting the pump.

13. A system for treating a patient, comprising:

a closed loop heat exchange catheter advanceable into the vasculature of the patient;

means for circulating patient coolant through the catheter and past a working fluid to lower the temperature of the patient to a target temperature;

means for deenergizing the pump;

means for maintaining the working fluid at a temperature of no more than approximately zero degrees Celsius; and

means for, upon indication of the patient'"'"'s temperature rising above target temperature, starting the pump.