Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
0 Assignments
0 Petitions
Accused Products
Abstract
Combinations of hydrophilic and hydrophobic entities in a biodegradable sustained release implant are shown to modulate each other'"'"'s rate of release. Formulations of a therapeutically active agent and modulator provide substantially constant rate of release for an extended period of time.
-
Citations
30 Claims
-
1-9. -9. (canceled)
- 10. A method for treating uveitis comprising placing at least one implant in the vitreal chamber of a patient'"'"'s eye afflicted with uveitis, the at least one implant comprising a matrix and an anti-inflammatory agent.
-
30. A method for treating uveitis comprising placing an extruded filament implant into the vitreal chamber of a patient'"'"'s eye afflicted with uveitis, the implant comprising a PLGA copolymer and an anti-inflammatory corticosteroid, wherein the implant is configured to release the anti-inflammatory agent over a period of up to about 6 weeks.
Specification