Method and device for delivering substance to tissue layers
First Claim
Patent Images
1. An apparatus comprising:
- an endoscope;
a flexible catheter adapted to be inserted via the endoscope to deliver a substance to a tissue from an internal aspect;
a penetrating member at a distal end of the catheter for penetrating the tissue, the penetrating member having a lumen in communication with the catheter, the lumen having an opening at a surface of the penetrating member to deliver the substance through the lumen; and
means for determining a location of the opening relative to the tissue.
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Abstract
A method and apparatus is described that includes a catheter and a penetrating member at a distal end of the catheter for penetrating a tissue. The penetrating member can have a lumen in communication with the catheter, the lumen having an opening at a surface of the penetrating member to deliver a substance through the lumen. The device includes means for determining a location of the opening relative to the tissue.
28 Citations
56 Claims
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1. An apparatus comprising:
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an endoscope;
a flexible catheter adapted to be inserted via the endoscope to deliver a substance to a tissue from an internal aspect;
a penetrating member at a distal end of the catheter for penetrating the tissue, the penetrating member having a lumen in communication with the catheter, the lumen having an opening at a surface of the penetrating member to deliver the substance through the lumen; and
means for determining a location of the opening relative to the tissue. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 33)
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20. An apparatus comprising:
a catheter having a first lumen for delivering a substance through the first lumen and having a second lumen for passing a fluid through the catheter; and
a member to monitor a flow-rate of the fluid through the second lumen, wherein the flow-rate of the fluid through the second lumen is used to determine a location of a distal opening of the first lumen relative to the tissue.- View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 34, 35)
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36. A method comprising:
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inserting a catheter into a body;
delivering a fluid through the catheter and monitoring a flow rate of the fluid out of an opening of the catheter;
inserting the catheter into a tissue; and
injecting a therapeutic material into the tissue through the catheter when it is determined that the flow rate is reduced, indicating that the opening of the catheter is located within the tissue. - View Dependent Claims (37, 38, 39, 40)
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41. A method comprising:
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inserting a catheter into a body;
delivering a fluid through a first lumen of the catheter;
monitoring a flow rate of the fluid or a pressure of the fluid within the first lumen;
inserting the catheter into a tissue; and
delivering a substance through the catheter when it is determined, by monitoring the flow rate or the pressure, that the catheter is properly located. - View Dependent Claims (42, 43, 44, 45, 46, 47, 48, 49)
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50. A method comprising:
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inserting a catheter into a body, the catheter having a penetrating member on a distal end of the catheter;
inserting a tip of the penetrating member into a tissue;
monitoring a pressure proximate the tip; and
delivering a substance through the penetrating member when the pressure indicates that the tip is properly located for the substance. - View Dependent Claims (51, 52, 53, 54, 55, 56)
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Specification