Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
First Claim
1. A therapeutic kit, comprising:
- a plurality of treatment strands configured to be implanted into a patient to a same depth;
wherein each said strand includes a distal end and a proximal end;
wherein each said strand includes one or more treatment seeds located between the distal and proximal ends of the strand;
wherein each of at least two said strands includes a custom distal end spacer provided between the distal end of the strand and the treatment seed located closest to the distal end of the strand;
wherein the custom distal end spacers in the at least two said strands cause the treatment seeds located closest to the distal ends of the strands to be spaced relative to the distal ends of the strands, according to a treatment plan, when the distal ends of the strands are implanted to the same depth using needles inserted to the same depth; and
wherein the custom distal end spacer of one said strand has a different length than the custom distal end spacer of a second said strand.
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Accused Products
Abstract
A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated strand made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the strand. The delivery system and method further customize the strand based on a prescription. The strands can have custom end spacings, which allow the optimal placing of seeds within the treatment tissue by implanting a plurality of strands to the same depth. A plurality of these strands can be implanted at the same time by the use of a guiding device.
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Citations
20 Claims
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1. A therapeutic kit, comprising:
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a plurality of treatment strands configured to be implanted into a patient to a same depth;
wherein each said strand includes a distal end and a proximal end;
wherein each said strand includes one or more treatment seeds located between the distal and proximal ends of the strand;
wherein each of at least two said strands includes a custom distal end spacer provided between the distal end of the strand and the treatment seed located closest to the distal end of the strand;
wherein the custom distal end spacers in the at least two said strands cause the treatment seeds located closest to the distal ends of the strands to be spaced relative to the distal ends of the strands, according to a treatment plan, when the distal ends of the strands are implanted to the same depth using needles inserted to the same depth; and
wherein the custom distal end spacer of one said strand has a different length than the custom distal end spacer of a second said strand. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A therapeutic kit, comprising:
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a plurality of treatment strands configured to be implanted into a patient;
wherein each said strand includes a distal end and a proximal end;
wherein each said strand includes one or more radioactive sources located between the distal and proximal ends of the strand;
wherein each of at least two said strands includes a custom distal end spacer provided between the distal end of the strand and the radioactive source located closest to the distal end of the strand;
wherein the custom distal end spacers in the at least two said strands cause the radioactive sources located closest to the distal ends of the strands to be spaced relative to the distal ends of the strands, according to a treatment plan, when the distal ends of the strands are implanted to the same depth; and
wherein the custom distal end spacer of one said strand has a different length than the custom distal end spacer of a second said strand. - View Dependent Claims (11)
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12. A method, comprising:
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accepting a tissue treatment plan for the tissue to be treated, which treatment plan specifies a number and spacing of treatment seeds to be provided in the treatment plan; and
creating a plurality of treatment strands, at least two of which includes a custom distal end spacer provided between the distal end of the strand and the treatment seed located closest to the distal end of the strand;
wherein the custom distal end spacers cause the treatment seeds located closest to the distal ends of the strands to be spaced relative to the distal end of the strands, according to the treatment plan, when the distal ends of the plurality of strands are implanted to a same depth; and
wherein at least two of the custom distal end spacers differ in length. - View Dependent Claims (13, 14)
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15. A method for treating a patient with a plurality of treatment strands, wherein each of at least two of the treatment strands has a custom distal end spacer between a distal end of the strand and the treatment seed located closest to the distal end of the strand, the method comprising:
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inserting a first needle to a first depth to thereby implant a first one of the strands to the first depth; and
inserting a plurality of further needles to the first depth, to thereby implant further strands, of the plurality of strands, to the first depth;
wherein the custom end spacers of at least two of the plurality of treatment strands have different lengths, thereby causing the seeds located closest to the distal ends of the at least two strands to be implanted to different depths. - View Dependent Claims (16)
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17. A method for treating a patient with a plurality of treatment strands, wherein each of at least two of the treatment strands has a custom distal end spacer between a distal end of the strand and the treatment seed located closest to the distal end of the strand, the method comprising:
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inserting a plurality of needles to a same depth, wherein each needle is loaded with one of the plurality of strands; and
implanting the plurality of strands to the same depth;
wherein the custom end spacers of at least two of the plurality of treatment strands have different lengths, thereby causing the seeds located closest to the distal ends of the at least two strands to be implanted to different depths. - View Dependent Claims (18)
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19. A method, comprising:
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accepting a tissue treatment plan for the tissue to be treated; and
creating the plurality of treatment strands, such that at least two of the strands includes a custom distal end spacer according to the treatment plan;
wherein the custom distal end spacers cause the treatment seeds located closest to distal ends of the treatment strands to be spaced relative to the distal ends of the treatment strands according to the treatment plan;
wherein the custom distal end spacers allow a health care professional to implant the strands to a uniform depth in the tissue to be treated; and
wherein at least two of the custom distal end spacers have different lengths. - View Dependent Claims (20)
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Specification