Method and apparatus for measuring blood sugar levels
First Claim
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1. A blood sugar level measurement apparatus comprising:
- a heat amount measurement portion for measuring a plurality of temperatures deriving from a body surface and obtaining information that is used for calculating the amount of convective heat transfer and the amount of radiation heat transfer, both of which are related to the dissipation of heat from said body surface;
an oxygen amount measurement portion for obtaining information relating to the blood oxygen amount, said oxygen amount measurement portion comprising a blood flow volume measurement portion for obtaining information relating to the blood flow volume, and an optical measurement portion for obtaining the hemoglobin concentration and the hemoglobin oxygen saturation in blood;
an openable and closable cover with which said optical measurement portion can be covered;
a cover open/close detection portion for detecting whether said cover is open or closed;
a memory portion in which a relationship between parameters associated with said plurality of temperatures and said blood oxygen amount, and blood sugar levels is stored;
a computation portion for converting a plurality of measurement values inputted from said heat amount measurement portion and said oxygen amount measurement portion into said parameters individually, and for computing a blood sugar level by applying said parameters to said relationship stored in said memory portion;
a display portion for displaying the result calculated by said computation portion; and
an optical sensor correction portion for correcting the output of said optical measurement portion, wherein;
said blood flow volume measurement portion comprises a body-surface contact portion, a first temperature detector disposed adjacent to said body-surface contact portion, a second temperature detector for detecting the temperature at a location spaced apart from said body-surface contact portion, and a heat-conducting member connecting said body-surface contact portion and said second temperature detector, and wherein;
said optical sensor correction portion comprises an optical correction check portion for calculating a correction value from the output of said optical measurement portion, and an optical correction portion for correcting the output of said optical measurement portion using the correction value calculated by said optical correction check portion.
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Abstract
A method and apparatus for non-invasively measuring blood sugar levels based on temperature measurement. A non-invasively determined blood sugar level measurement value is corrected on the basis of the blood oxygen saturation value and the blood flow volume, thereby stabilizing measurement data. A measurement portion is provided with a cover with which the measurement portion can be covered and protected when not in use. By controlling the opening and closing of the cover, erroneous measurement can be prevented. The intensity of a detection signal in an optical system is corrected by a circuit.
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Citations
22 Claims
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1. A blood sugar level measurement apparatus comprising:
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a heat amount measurement portion for measuring a plurality of temperatures deriving from a body surface and obtaining information that is used for calculating the amount of convective heat transfer and the amount of radiation heat transfer, both of which are related to the dissipation of heat from said body surface;
an oxygen amount measurement portion for obtaining information relating to the blood oxygen amount, said oxygen amount measurement portion comprising a blood flow volume measurement portion for obtaining information relating to the blood flow volume, and an optical measurement portion for obtaining the hemoglobin concentration and the hemoglobin oxygen saturation in blood;
an openable and closable cover with which said optical measurement portion can be covered;
a cover open/close detection portion for detecting whether said cover is open or closed;
a memory portion in which a relationship between parameters associated with said plurality of temperatures and said blood oxygen amount, and blood sugar levels is stored;
a computation portion for converting a plurality of measurement values inputted from said heat amount measurement portion and said oxygen amount measurement portion into said parameters individually, and for computing a blood sugar level by applying said parameters to said relationship stored in said memory portion;
a display portion for displaying the result calculated by said computation portion; and
an optical sensor correction portion for correcting the output of said optical measurement portion, wherein;
said blood flow volume measurement portion comprises a body-surface contact portion, a first temperature detector disposed adjacent to said body-surface contact portion, a second temperature detector for detecting the temperature at a location spaced apart from said body-surface contact portion, and a heat-conducting member connecting said body-surface contact portion and said second temperature detector, and wherein;
said optical sensor correction portion comprises an optical correction check portion for calculating a correction value from the output of said optical measurement portion, and an optical correction portion for correcting the output of said optical measurement portion using the correction value calculated by said optical correction check portion. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A blood sugar level measurement apparatus comprising:
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an ambient temperature measurement portion for measuring ambient temperature;
a body-surface contact portion with which a body surface comes into contact;
an adjacent temperature detector disposed adjacent to said body-surface contact portion;
a radiation heat detector for measuring radiation heat from said body surface;
a heat conducting member disposed adjacent to said body-surface contact portion;
an indirect temperature detector disposed in contact with said heat conducting member and at the same time spaced apart from said body-surface contact portion, for detecting the temperature at said location spaced apart from said body-surface contact portion;
an optical measurement portion comprising a light source for irradiating said body-surface contact portion with light of at least two different wavelengths, and a photodetector;
an openable and closable cover with which said optical measurement portion can be covered;
a cover open/close detection portion for detecting whether said cover is open or closed;
a computation portion comprising a conversion portion and a processing portion, said conversion portion converting the outputs from said adjacent temperature detector, said indirect temperature detector, said ambient temperature measurement portion, said radiation heat detector, and said photodetector, into individual parameters, and said processing portion storing a relationship between said parameters and blood sugar levels in advance and calculating a blood sugar level by applying said parameters to said relationship;
an optical sensor correction portion for correcting the output of said photodetector; and
a display portion for displaying the result outputted from said computation portion, wherein;
said optical sensor correction portion comprises an optical correction check portion for calculating a correction value based on the output of said photodetector, and an optical correction portion for correcting the output of said photodetector using the correction value calculated by said optical correction check portion. - View Dependent Claims (8, 9, 10, 11, 12)
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13. A blood sugar level measurement apparatus comprising:
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an ambient temperature measurement portion for measuring ambient temperature;
a body-surface contact portion with which a body surface comes into contact;
an adjacent temperature detector disposed adjacent to said body-surface contact portion;
a radiation heat detector for measuring radiation heat from said body surface;
a heat conducting member disposed in contact with said body-surface contact portion;
an indirect temperature detector disposed adjacent to said heat conducting member and at the same time spaced apart from said body-surface contact portion, for detecting the temperature at said location spaced apart from said body-surface contact portion;
an optical measurement portion comprising a light source for irradiating said body-surface contact portion with light of at least two different wavelengths, and a photodetector;
an openable and closable cover comprising a reflector on the back surface thereof, said cover enabling said optical measurement portion to be covered, said reflector being used for the correction of said optical measurement portion;
a cover open/close detection portion for detecting whether said cover is open or closed;
a computation portion comprising a conversion portion and a processing portion, said conversion portion converting the outputs from said adjacent temperature detector, said indirect temperature detector, said ambient temperature measurement portion, said radiation heat detector, and said photodetector, into individual parameters, and said processing portion storing a relationship between said parameters and blood sugar levels in advance and calculating a blood sugar level by applying said parameters to said relationship; and
a display portion for displaying the result outputted from said computation portion. - View Dependent Claims (14, 15)
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16. A blood sugar level measurement method comprising the steps of:
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confirming that a measurement opening portion of an optical measurement portion is closed by a cover comprising a reflector disposed on the surface thereof, said optical measurement portion comprising a light source for emitting light of a plurality of wavelengths and a photodetector;
obtaining a first measurement value by detecting the output of said photodetector without said light source emitting light;
obtaining a second measurement value by detecting the output of said photodetector when said light with said plurality of wavelengths is emitted in a sequential manner;
calculating a characteristics coefficient for each wavelength on the basis of said first and said second measurement values;
comparing said characteristics coefficient with an initial value that is measured and stored in advance, for each of said plurality of wavelengths, and then determining and storing a correction value if a fluctuation amount of said characteristics coefficient with respect to said initial value exceeds a preset threshold;
irradiating a test subject positioned at said measurement opening portion with the light of said plurality of wavelengths from said light source, and obtaining a third measurement value by detecting the output of said detector for each wavelength;
correcting said third measurement value for a corresponding wavelength using said correction value if said correction value is stored; and
determining information regarding hemoglobin concentration and information regarding hemoglobin oxygen saturation on the basis of said third measurement value that has been corrected by said correction value. - View Dependent Claims (17, 18, 19, 20, 21, 22)
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Specification