Quantitative chronological medical infusion device

• US 20060079831A1
• Filed: 08/18/2004
• Published: 04/13/2006
• Est. Priority Date: 08/18/2004
• Status: Abandoned Application

• Current Assignee: Bionica International Incorporated (Bionica Incorporated)
• Original Assignee: Bionica International Incorporated (Bionica Incorporated)
• Inventors: Gilbert, Gregory Ford
• Application Number:
  US10/834,466
• Publication Number:
  US 20060079831A1
• Time in Patent Office: Days
• US Class Current: 604/31
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

The present invention is a medical infusion and aspiration system delivering precisely timed and accurately calculated, adjusted pulsated delivery in high rates of flow delivering an effective profile of pulses tailored to provide momentary spikes of levels of freely available medicines based upon the uptake of the medicine and optimally on real time measurements of the medicine or response of the patient, termed Quantitative Chronological Delivery. The system comprises any pumping mechanism, and optimally a pumping mechanism, and a cassette or cartridge having a reservoir area where the plunger rotates as it advances in reference to the cartridge to provide additional accuracy and overcome the forces of inertia and slip-stick as well as eliminate backlash. Optimally, the systems incorporates an encoded area and an opening for connection to an infusion tube with an in-line sensor area where sampling probes are located. The infusion is adjusted in both amount and duration between pulses to provide quantitatively controlled, chronologically optimized infusion. A motor causes bi-directional pumping to allow for samples to be presented to the sensor area. The system accuracy allows for more concentrated medicines, as a sealed container can eliminate the need for diluting or withdrawing medicine to load a reservoir, and achieves extraordinary accuracy without error correcting software or expensive volumetric measurement and control systems.

Claims

1. A medical infusion and aspiration system, for accurate Quantitative Chronological Delivery of timed and individually controlled pulses using the known bioavailability uptake data of any infused medicine to deliver the optimal pluses which control or enhance the bioavailability or effectiveness of that medicine, and through pulse delivery, enhance the bioavailability or effectiveness by changing the duration between pulses and amount infused during each pulse irrespective of the existing baseline levels of the medicine, which pulses are delivered by any conventional means of pumping.

2. The medical infusion device as in claim 1 containing:

at least one cassette having a cartridge, a housing and a plunger, the cartridge having a cylindrical shape, an outer cartridge surface, and a reservoir area;

the outer cartridge surface having a grooved or threaded surface;

an attachment for an infusion tube;

a pumping mechanism having a gear linkage, a motor and a pumping device delivering a pulsatile infusion; and

an attachment for an in-line sensor probe.

3. The medical infusion and aspiration system of claim 2, wherein the outer cartridge surface is in threaded relationship to the housing inner threaded surface.

4. The medical infusion and aspiration system of claim 2, wherein the infusion tube is connectively coupled to the plunger opening.

5. The medical infusion and aspiration system of claim 2, wherein the cartridge is configured to receive a cap and a container top.

6. The medical infusion and aspiration system of claim 2, wherein the housing has no fewer than one and a plurality of openings parallel to the central axis of the housing;

the plurality of openings allows for trapped air to be exhausted and creates an inspection window.

7. The medical infusion and aspiration system of claim 2, wherein the bottom surface of the cartridge and housing have lips or ridges to receive a removable cover.

8. The medical infusion and aspiration system of claim 2, wherein the encoded area comprises an optical or electromagnetic strip.

9. The medical infusion and aspiration system of claim 2, further comprising a mechanism capable of reading the encoded area.

10. The medical infusion and aspiration system of claim 2, wherein the stanchion is aligned with the central axis of the housing and configured to capture the plunger fit within the reservoir area.

11. The medical infusion and aspiration system of claim 2, wherein the gear linkage connectively couples the motor to the piston or to the cartridge outer surface.

12. The medical infusion and aspiration system of claim 11, wherein the motor causes both lateral and axial rotation of the plunger.

13. The medical infusion and aspiration system of claim 2, wherein the lateral and axial rotation of the plunger is bi-directional allowing for both infusion and aspiration.

14. The medical infusion and aspiration system of claim 2, wherein the in-line sensor probe is located in the infusion tube.

15. The medical infusion and aspiration system of claim 14, wherein the in-line sensor probe determines a chemical component or level of substrates in an aspirated fluid.

16. The medical infusion and aspiration system of claim 2, wherein the pumping device has at least one source of information input.

17. The medical infusion and aspiration system of claim 2, wherein the information provided adjusts the duration between pulses and amount of fluid pulsed to provide Quantitative Chronological Delivery changes to stimulate certain tissues with less active ingredient.

18. The medical infusion and aspiration system of claim 2, wherein the at least one cassette comprises at least two cassettes.

19. The medical infusion and aspiration system of claim 2, wherein the at least two cassettes are coupled and driven independently or in mechanical linkage.