Hyaluronic acid in the enhancement of lens regeneration
First Claim
1. A method for enhancing regeneration of lens cells in a mammal, comprising:
- filling a lens capsule bag of said mammal with a composition comprising hyaluronic acid, and after formation of a ring of lens tissue, administering hyaluronidase into the capsular bag.
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Accused Products
Abstract
The present invention addresses the treatment of ocular conditions by the enhancement of lens regeneration. This is accomplished by the administration of a high viscosity composition including a hyaluronic acid compound. Excess high viscosity composition may be removed by focal laser photophacoablation or through the use of a digestive compound or enzyme such as hyaluronidase. Additionally, a collagen product may be injected within the lens capsule to improve lens cell proliferation and differentiation, and to improve the configuration, shape and structure of regenerated lenses. Various embodiments involving the enhancement of lens regeneration are described. For example, lens regeneration may be enhanced by filling the lens capsule bag with the inventive hyaluronic acid compound; by inserting at least one collagen patch in the lens capsule; and/or by injecting a collagen-based product into the lens capsule.
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Citations
23 Claims
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1. A method for enhancing regeneration of lens cells in a mammal, comprising:
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filling a lens capsule bag of said mammal with a composition comprising hyaluronic acid, and after formation of a ring of lens tissue, administering hyaluronidase into the capsular bag. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for treating an ocular condition, comprising:
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providing a first composition comprising hyaluronic acid;
inserting said first composition into a lens capsule bag to enhance regeneration of lens cells, thereby treating said ocular condition; and
after formation of a ring of lens tissue, inserting a second composition into the lens capsule bag to dissolve the first composition. - View Dependent Claims (8, 9, 10, 11, 12, 13)
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14. A method for enhancing regeneration of lens cells in a mammal, comprising:
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providing a polymeric composition;
filling a lens capsule bag of said mammal with said composition, and administering an enzymatic compound into the lens capsule bag. - View Dependent Claims (15, 16)
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17. A method for enhancing regeneration of lens cells in a mammal, comprising:
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filling a lens capsule bag of said mammal with a composition comprising hyaluronic acid, waiting a period of time sufficient for formation of a ring of lens tissue; and
administering hyaluronidase into the capsular bag. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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Specification