Convertible extracorporeal blood perfusion systems

• US 20060089586A1
• Filed: 10/19/2005
• Published: 04/27/2006
• Est. Priority Date: 10/22/2004
• Status: Abandoned Application

• Current Assignee: Sorin Group USA Incorporated (LivaNova Plc)
• Original Assignee: Sorin Group USA Incorporated (LivaNova Plc)
• Inventors: Rawles, Thomas A., Kaus, Stanley B., Litzie, Anthony Kenneth
• Application Number:
  US11/254,227
• Publication Number:
  US 20060089586A1
• Time in Patent Office: Days
• US Class Current: 604/4.10
• CPC Class Codes: A61M 1/1698 Blood oxygenators with or without heat-exchangers intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 1/3666 Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
• CPC Class Codes: A61M 1/3667 with assisted venous return

Abstract

A convertible extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure including: a closed-loop cardiopulmonary bypass system; and a circuit for converting between the closed-loop cardiopulmonary bypass system and a cardiopulmonary bypass system containing a venous reservoir, the circuit for converting comprising a venous reservoir that can be fluidly connected to a venous line from the patient and that can be fluidly connected to the inlet of a first pump, the first pump being part of the closed-loop cardiopulmonary bypass system, the closed loop cardiopulmonary bypass system comprising a bubble removal device fluidly connected to the inlet of the first pump.

Claims

1. A convertible extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure comprising:

a closed-loop cardiopulmonary bypass system; and

a circuit for converting between the closed-loop cardiopulmonary bypass system and a cardiopulmonary bypass system containing a venous reservoir,

the circuit for converting comprising a venous reservoir that can be fluidly connected to a venous line from the patient and that can be fluidly connected to the inlet of a first pump, the first pump being part of the closed-loop cardiopulmonary bypass system,

the closed-loop cardiopulmonary bypass system comprising a bubble removal device fluidly connected to the inlet of the first pump.

2. A convertible extracorporeal blood perfusion system of claim 1, further comprising a bubble sensor on the venous line from the patient that is operable to send a signal when gaseous bubbles are detected to a controller that automatically activates a second pump fluidly attached to the bubble removal device in order to purge air from the bubble removal device and venous line.

3. A convertible extracorporeal blood perfusion system of claim 1, further comprising a bubble sensor on a first pump inlet line to the inlet of the first pump that is operable to send a signal when bubbles are detected in the first pump inlet line to a controller that automatically closes a clamp on an arterial line to the patient in order to stop the flow of blood back to the patient.

4. A convertible extracorporeal blood perfusion system of claim 1, wherein the venous reservoir is a soft bag venous reservoir.

5. A convertible extracorporeal blood perfusion system of claim 4, wherein the venous reservoir bag is capable of vacuum assisted venous drainage.

6. A convertible extracorporeal blood perfusion system of claim 1, wherein the venous reservoir is a hardshell venous reservoir.

7. A convertible extracorporeal blood perfusion system of claim 6, wherein the hardshell venous reservoir is capable of vacuum assisted venous drainage.

8. A convertible extracorporeal blood perfusion system of claim 1, wherein the closed-loop cardiopulmonary bypass system comprises an oxygenator and a heat exchanger.

9. A convertible extracorporeal blood perfusion system of claim 8, wherein the bubble removal device, first pump, oxygenator, and heat exchanger are integrated in one unit.

10. A convertible extracorporeal blood perfusion system of claim 1, wherein the closed-loop cardiopulmonary bypass system comprises an oxygenator, a heat exchanger, and an arterial filter.

11. A convertible extracorporeal blood perfusion system of claim 10, wherein the bubble removal device, first pump, oxygenator, heat exchanger, and arterial filter are integrated in one unit.

12. A convertible extracorporeal blood perfusion system of claim 1, further comprising a level sensor that is operable to detect a blood level in the venous reservoir that is below a predetermined level and is operable to send a signal to a controller that automatically stops the flow of blood from the venous reservoir.

13. A convertible extracorporeal blood perfusion system of claim 12, wherein the controller automatically stops the flow of blood from the venous reservoir by closing a clamp on a venous reservoir exit line.

14. A convertible extracorporeal blood perfusion system of claim 12, wherein the controller automatically stops the flow of blood from the venous reservoir by stopping a second pump on a venous reservoir exit line.

15. A convertible extracorporeal blood perfusion system of claim 12, wherein the controller automatically stops the flow of blood from the venous reservoir by closing a clamp on an arterial line to the patient.

16. A convertible extracorporeal blood perfusion system of claim 1, further comprising a level sensor that is operable to detect a blood level in the venous reservoir that is below a predetermined level and is operable to send a signal to a controller that automatically closes a clamp on an arterial line to the patient in order to stop the flow of blood to the patient.

17. A convertible extracorporeal blood perfusion system of claim 1, further comprising a level sensor that is operable to detect a blood level in the venous reservoir that is above a predetermined level and is operable to send a signal to a controller that automatically starts the flow of blood from the venous reservoir.

18. A convertible extracorporeal blood perfusion system of claim 17, wherein the controller automatically starts the flow of blood from the venous reservoir by opening a clamp on a venous reservoir exit line.

19. A convertible extracorporeal blood perfusion system of claim 17, wherein the controller automatically starts the flow of blood from the venous reservoir by starting a second pump on a venous reservoir exit line.

20. A convertible extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure comprising:

a closed-loop cardiopulmonary bypass system; and

a circuit for converting between the closed-loop cardiopulmonary bypass system and a cardiopulmonary bypass system containing a venous reservoir,

the circuit for converting comprising a venous reservoir that can be fluidly connected to a venous line from the patient and that can be fluidly connected to the inlet of a first pump, the first pump being part of the closed-loop cardiopulmonary bypass system,

the convertible extracorporeal blood perfusion system comprising a level sensor that is operable to detect a blood level in the venous reservoir that is below a predetermined level and is operable to send a signal to a controller that automatically stops the flow of blood from the venous reservoir.

21. A convertible extracorporeal blood perfusion system of claim 20, wherein the controller automatically stops the flow of blood from the venous reservoir by closing a clamp on a venous reservoir exit line.

22. A convertible extracorporeal blood perfusion system of claim 20, wherein the controller automatically stops the flow of blood from the venous reservoir by stopping a second pump on a venous reservoir exit line.

23. A convertible extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure comprising:

a closed-loop cardiopulmonary bypass system; and

a circuit for converting between the closed-loop cardiopulmonary bypass system and a cardiopulmonary bypass system containing a venous reservoir,

the circuit for converting comprising a venous reservoir that can be fluidly connected to a venous line from the patient and that can be fluidly connected to the inlet of a first pump, the first pump being part of the closed-loop cardiopulmonary bypass system,

the convertible extracorporeal blood perfusion system comprising a level sensor that is operable to detect a blood level in the venous reservoir that is below a predetermined level and is operable to send a signal to a controller that automatically closes a clamp on an arterial line to the patient in order to stop the flow of blood from the venous reservoir and the flow of blood to the patient.

24. A method for converting a convertible extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure from a closed-loop cardiopulmonary bypass system to a cardiopulmonary bypass system containing a venous reservoir, wherein the convertible extracorporeal blood perfusion system comprises:

a closed-loop cardiopulmonary bypass system; and

a circuit for converting between the closed-loop cardiopulmonary bypass system and a cardiopulmonary bypass system containing a venous reservoir,

the circuit for converting comprising a venous reservoir that can be fluidly connected to a venous line from the patient and that can be fluidly connected to the inlet of a first pump, the first pump being part of the closed-loop cardiopulmonary bypass system,

the closed-loop cardiopulmonary bypass system comprising a bubble removal device fluidly connected to the inlet of the first pump,

the method comprising fluidly connecting the venous reservoir to the venous line from the patient and fluidly connecting the venous reservoir to the inlet of the first pump.

25. A method of claim 24, wherein the convertible extracorporeal blood perfusion system further comprises a bubble sensor on the venous line from the patient that is operable to send a signal when gaseous bubbles are detected to a controller that automatically activates a second pump fluidly attached to the bubble removal device in order to purge air from the bubble removal device and venous line.

26. A method of claim 24, wherein the convertible extracorporeal blood perfusion system further comprises a bubble sensor on a first pump inlet line to the inlet of the first pump that is operable to send a signal when bubbles are detected in the first pump inlet line to a controller that automatically closes a clamp on an arterial line to the patient in order to stop the flow of blood back to the patient.

27. A method of claim 24, wherein the venous reservoir is a soft bag venous reservoir.

28. A method of claim 27, wherein the venous reservoir bag is capable of vacuum assisted venous drainage.

29. A method of claim 24, wherein the venous reservoir is a hardshell venous reservoir.

30. A method of claim 29, wherein the hardshell venous reservoir is capable of vacuum assisted venous drainage.

31. A method of claim 24, wherein the closed-loop cardiopulmonary bypass system comprises an oxygenator and a heat exchanger.

32. A method of claim 31, wherein the bubble removal device, first pump, oxygenator, and heat exchanger are integrated in one unit.

33. A method of claim 24, wherein the closed-loop cardiopulmonary bypass system comprises an oxygenator, a heat exchanger, and an arterial filter.

34. A method of claim 33, wherein the bubble removal device, first pump, oxygenator, heat exchanger, and arterial filter are integrated in one unit.

35. A method of claim 24, wherein the convertible extracorporeal blood perfusion system comprises a level sensor that is operable to detect a blood level in the venous reservoir that is below a predetermined level and is operable to send a signal to a controller that automatically stops the flow of blood from the venous reservoir.

36. A method of claim 35, wherein the controller automatically stops the flow of blood from the venous reservoir by closing a clamp on a venous reservoir exit line.

37. A method of claim 35, wherein the controller automatically stops the flow of blood from the venous reservoir by stopping a second pump on a venous reservoir exit line.

38. A method of claim 35, wherein the controller automatically stops the flow of blood from the venous reservoir by closing a clamp on an arterial line to the patient.

39. A method of claim 24, wherein the convertible extracorporeal blood perfusion system comprises a level sensor that is operable to detect a blood level in the venous reservoir that is below a predetermined level and is operable to send a signal to a controller that automatically closes a clamp on an arterial line to the patient in order to stop the flow of blood to the patient.

40. A method of claim 24, wherein the convertible extracorporeal blood perfusion system comprises a level sensor that is operable to detect a blood level in the venous reservoir that is above a predetermined level and is operable to send a signal to a controller that automatically starts the flow of blood from the venous reservoir.

41. A method of claim 40, wherein the controller automatically starts the flow of blood from the venous reservoir by opening a clamp on a venous reservoir exit line.

42. A method of claim 40, wherein the controller automatically starts the flow of blood from the venous reservoir by starting a second pump on a venous reservoir exit line.