Compositions for treatment with glucagon-like peptide, and methods of making and using the same
First Claim
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1. A biocompatible composition comprising:
- a carrier with a metal binding domain (MBD), a metal ion chelated to the metal binding domain of the carrier, and glucagon-like peptide-1 (GLP-1) with a MBD chelated to the metal ion, wherein after administration of the composition to a patient, GLP-1 is released from the carrier.
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Abstract
In part, the present invention is directed to compositions comprising a carrier with a metal binding domain, a metal ion, and GLP-1.
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Citations
22 Claims
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1. A biocompatible composition comprising:
- a carrier with a metal binding domain (MBD), a metal ion chelated to the metal binding domain of the carrier, and glucagon-like peptide-1 (GLP-1) with a MBD chelated to the metal ion, wherein after administration of the composition to a patient, GLP-1 is released from the carrier.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. The pharmaceutical composition of claim 22, wherein the pharmaceutical composition is an injectable composition.
Specification