Medication delivery apparatus and methods for intravenous infusions

• US 20060100578A1
• Filed: 09/13/2004
• Published: 05/11/2006
• Est. Priority Date: 09/13/2004
• Status: Abandoned Application

• Current Assignee: Ivenix, Inc. (Fresenius SE & Co. KGaA)
• Original Assignee: Tandem Medical, Inc.
• Inventors: Lieberman, Marc S.
• Application Number:
  US10/939,979
• Publication Number:
  US 20060100578A1
• Time in Patent Office: Days
• US Class Current: 604/132
• CPC Class Codes: A61J 1/05 for collecting, storing or administering blood, plasma or medical fluids multiple bags systems for separating or storing blood components A61M1/0209; Infusion or perfusion containers
• CPC Class Codes: A61M 2005/14506 mechanically driven, e.g. spring or clockwork
• CPC Class Codes: A61M 2205/17 with redundant control systems
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/1409 in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems needle sets A61M5/162
• CPC Class Codes: A61M 5/148 flexible, e.g. independent bagsA61M5/155 takes precedence
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407

Abstract

The present invention relates to delivery containers designed to deliver fluids for infusion to patients in a predetermined sequence, and methods for their construction and use. The containers described herein integrally comprise a plurality of non-fluidly connected chambers. The containers may be configured to deliver a volume of each medication of an infusion therapy in a predetermined sequence, duration, and/or interval from these chambers; alternatively, a container may be part of a larger device that provides the necessary hardware to perform such predetermined delivery. The container provides improved infusion therapy administration by reducing opportunities for error, infection, adverse drug interactions, or other complications.

Claims

1. A method of providing a therapy regimen to a patient, said therapy regimen comprising the delivery in a predetermined sequence of a plurality of fluids from an integral container to said patient, said integral container comprising said plurality of fluids contained within separate non-fluidly connected chambers, the method comprising:

delivering said plurality of fluids from said separate non-fluidly connected chambers to said patient in said predetermined sequence.

2. The method of claim 1, wherein said plurality of fluids are delivered in a predetermined sequence by exerting positive pressure on said separate non-fluidly connected chambers, whereby said fluids are expressed from said chambers in said predetermined sequence.

3. The method of claim 2, wherein said positive pressure is created by compression of said separate non-fluidly connected chambers in a predetermined sequence.

4. The method of claim 1, wherein said plurality of fluids are delivered in a predetermined sequence by exerting negative pressure on said separate non-fluidly connected chambers, whereby said fluids are extracted from said chambers in said predetermined sequence.

5. The method of claim 4, wherein said negative pressure is created by pumping said fluids from said separate non-fluidly connected chambers in a predetermined sequence.

6. The method of claim 5, wherein negative pressure is exerted on each said separate non-fluidly connected chamber by a separate pump.

7. The method of claim 6, wherein each said separate pump is controlled by a programmable interface.

8. The method of claim 1, wherein said plurality of fluids are delivered in a predetermined sequence by gravity feed from said separate non-fluidly connected chambers, whereby said fluids flow from said chambers in said predetermined sequence.

9. The method of claim 8, wherein said plurality of fluids are delivered in a predetermined sequence by a differential hydrostatic head height in two or more separate non-fluidly connected chambers.

10. The method of claim 1, wherein said plurality of fluids flow from said separate non-fluidly connected chambers to a manifold comprising a separate input port in fluid communication with each said separate non-fluidly connected chamber and at least one common port, whereby said fluids flow to said common port in said predetermined sequence.

11. The method of claim 1, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by valves.

12. The method of claim 1, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by an active control device.

13. The method of claim 1, wherein flow from one or more of said separate non-fluidly connected chambers is controlled by a passive control device.

14. The method of claim 1, wherein two or more chambers in said integral container become fluidly connected prior to or during delivery of said plurality of fluids, whereby a single chamber is formed.

15. A fluid delivery device, comprising:

an integral container comprising a plurality of fluids contained within separate non-fluidly connected chambers;

wherein said fluid delivery device is configured and arranged to deliver said plurality of fluids from said separate non-fluidly connected chambers to said at least one common port in a predetermined sequence.

16. The fluid delivery device of claim 15, further comprising a manifold comprising a separate input port in fluid communication with each said separate non-fluidly connected chamber and at least one common port.

17. The fluid delivery device of claim 15, further comprising one or more pumping elements.

18. A medication delivery system, comprising:

a bag having;

at least one chamber containing a medication fluid, and a manifold; and

a pump having an activating mechanism configured to activate said chamber(s) to dispense said fluid from the bag.

19. A fluid delivery container, comprising:

a bag having at least one fluid chamber; and

structure for minimizing pressure drop between the chamber and an associated conduit upon the application of pressure to the chamber.

20. A fluid delivery pump, comprising:

a structure for sequentially applying constant force to compress a flexible fluid container from a first end towards a second end of said container; and

an energy absorption device coupled to the structure for sequentially applying constant force for limiting the maximum rate at which said structure compresses the fluid container.