System and method for the treatment of reperfusion injury
First Claim
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1. A method for treating an infarct of a heart in a human patient following reperfusion comprising:
- inserting a catheter into a coronary artery of the patient wherein the catheter includes a proximal region and a distal region and the distal region further comprises an expandable member, and cyclically expanding and reducing the expandable member to modulate the distal coronary blood flow.
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Abstract
A method and apparatus for the prevention and treatment of reperfusion injury following the reperfusion of acute MI which includes modulation of coronary blood flow or oxygen delivery following the reperfusion of the infarct with a catheter placed in the coronary artery or vein.
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Citations
20 Claims
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1. A method for treating an infarct of a heart in a human patient following reperfusion comprising:
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inserting a catheter into a coronary artery of the patient wherein the catheter includes a proximal region and a distal region and the distal region further comprises an expandable member, and cyclically expanding and reducing the expandable member to modulate the distal coronary blood flow. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for treating a reperfusion injury of an organ in a human patient resulting from an occluded artery comprising:
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opening the occluded artery;
reperfusing the organ;
inserting a catheter into the artery the catheter having a proximal region, a distal region and an expandable member attached to the distal region, and repeatedly expanding and reducing the expandable member. - View Dependent Claims (10, 11)
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12. A method for treating an infarct of a heart in a human patient following reperfusion comprising:
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inserting a catheter into a coronary artery of the heart of the patient, and infusing into the coronary artery a perfusate with reduced oxygen content. - View Dependent Claims (13, 14, 15)
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16. A method for treating a reperfusion injury of an organ in a human patient resulting from an occluded artery during acute myocardial infarction (MI) comprising:
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opening the occluded artery in response to the MI;
positioning a balloon catheter in the re-opened coronary vessel, and modulating a size of the balloon catheter to modulate arterial coronary blood flow distal of the re-opened occlusion. - View Dependent Claims (18, 19, 20)
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17. The method of claim 17 wherein the balloon modulates venous coronary blood flow in the coronary sinus.
Specification