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Apparatus and method for in-vivo plasmapheresis using periodic backflush containing anticoagulant

  • US 20060106331A1
  • Filed: 12/29/2005
  • Published: 05/18/2006
  • Est. Priority Date: 01/04/2001
  • Status: Active Grant
First Claim
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1. A method of carrying out human or animal in-vivo plasmapheresis comprising:

  • implanting a filter device within a blood vessel of a patient, said filter device comprising a plurality of elongated hollow microporous fibers;

    providing a catheter in fluid communication with the hollow interior of said fibers, and diff-using plasma and toxins from the patient'"'"'s blood through the wall of said fibers into the hollow interior thereof; and

    periodically interrupting said diffusion of plasma and toxins and backflushing said fibers by directing a backflush fluid containing an amount of anticoagulant at least sufficient to provide fiber thromboresistance through said catheter into said fibers at a pressure and for an interval sufficient to substantially clear the pores of said filter, and after said interval, resuming said diffusion of plasma.

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